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Last Name
Institution

Ernst J. Schaefer

TitleProfessor
InstitutionHuman Nutrition Research Center
DepartmentMedicine
AddressLipid Research Laboratory
Human Nutrition Research Center
711 Washington Street, Box 216
Boston MA 02111
Phone(617) 556-3100
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Asztalos IB, Gleason JA, Sever S, Gedik R, Asztalos BF, Horvath KV, Dansinger ML, Lamon-Fava S, Schaefer EJ. Effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular disease risk factors: a randomized clinical trial. Metabolism. 2016 Nov; 65(11):1636-1645. PMID: 27733252.
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    2. Schaefer EJ, Anthanont P, Diffenderfer MR, Polisecki E, Asztalos BF. Diagnosis and treatment of high density lipoprotein deficiency. Prog Cardiovasc Dis. 2016 Sep - Oct; 59(2):97-106. PMID: 27565770.
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    3. Hauser TH, Salastekar N, Schaefer EJ, Desai T, Goldfine HL, Fowler KM, Weber GM, Welty F, Clouse M, Shoelson SE, Goldfine AB. Effect of Targeting Inflammation With Salsalate: The TINSAL-CVD Randomized Clinical Trial on Progression of Coronary Plaque in Overweight and Obese Patients Using Statins. JAMA Cardiol. 2016 Jul 1; 1(4):413-23. PMID: 27438317.
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    4. Sato K, Okajima F, Miyashita K, Imamura S, Kobayashi J, Stanhope KL, Havel PJ, Machida T, Sumino H, Murakami M, Schaefer E, Nakajima K. The majority of lipoprotein lipase in plasma is bound to remnant lipoproteins: A new definition of remnant lipoproteins. Clin Chim Acta. 2016 Oct 1; 461:114-25. PMID: 27342999.
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    5. Tsunoda F, Asztalos IB, Horvath KV, Steiner G, Schaefer EJ, Asztalos BF. Fenofibrate, HDL, and cardiovascular disease in Type-2 diabetes: The DAIS trial. Atherosclerosis. 2016 Apr; 247:35-9. PMID: 26854974.
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    6. Diffenderfer MR, Lamon-Fava S, Marcovina SM, Barrett PH, Lel J, Dolnikowski GG, Berglund L, Schaefer EJ. Distinct metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein(a). Metabolism. 2016 Apr; 65(4):381-90. PMID: 26975530.
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    7. Karl JP, Roberts SB, Schaefer EJ, Gleason JA, Fuss P, Rasmussen H, Saltzman E, Das SK. Effects of carbohydrate quantity and glycemic index on resting metabolic rate and body composition during weight loss. Obesity (Silver Spring). 2015 Nov; 23(11):2190-8. PMID: 26530933.
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    8. Hsu P, Ai M, Kanda E, Yu NC, Chen HL, Chen HW, Cheng MH, Kohzuma T, Schaefer EJ, Yoshida M. A comparison of glycated albumin and glycosylated hemoglobin for the screening of diabetes mellitus in Taiwan. Atherosclerosis. 2015 Sep; 242(1):327-33. PMID: 26247684.
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    9. Pullinger CR, Stock EO, Movsesyan I, Malloy MJ, Frost PH, Tripuraneni R, Quinn AG, Ishida BY, Schaefer EJ, Asztalos BF, Kane JP. Identification and metabolic profiling of patients with lysosomal acid lipase deficiency. J Clin Lipidol. 2015 Sep-Oct; 9(5):716-726.e1. PMID: 26350820.
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    10. Tsunoda F, Lamon-Fava S, Asztalos BF, Iyer LK, Richardson K, Schaefer EJ. Effects of oral eicosapentaenoic acid versus docosahexaenoic acid on human peripheral blood mononuclear cell gene expression. Atherosclerosis. 2015 Aug; 241(2):400-8. PMID: 26074314.
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    11. He ZH, D'Eon SA, Tinsley LJ, Fitzgerald S, Hastings SM, Khamaisi M, Sun JK, Turek SJ, Schaefer EJ, King GL, Keenan HA. Cardiovascular disease protection in long-duration type 1 diabetes and sex differences. Diabetes Care. 2015 May; 38(5):e73-4. PMID: 25908159.
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    12. Le NA, Diffenderfer MR, Thongtang N, Ooi EM, Barrett PH, Horvath KV, Dolnikowski GG, Asztalos BF, Schaefer EJ, Brown WV. Rosuvastatin Enhances the Catabolism of LDL apoB-100 in Subjects with Combined Hyperlipidemia in a Dose Dependent Manner. Lipids. 2015 May; 50(5):447-58. PMID: 25809021.
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    13. Ikezaki H, Furusyo N, Ihara T, Hayashi T, Ura K, Hiramine S, Mitsumoto F, Takayama K, Murata M, Kohzuma T, Ai M, Schaefer EJ, Hayashi J. Glycated albumin as a diagnostic tool for diabetes in a general Japanese population. Metabolism. 2015 Jun; 64(6):698-705. PMID: 25817605.
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    14. Anthanont P, Asztalos BF, Polisecki E, Zachariah B, Schaefer EJ. Case report: A novel apolipoprotein A-I missense mutation apoA-I (Arg149Ser)Boston associated with decreased lecithin-cholesterol acyltransferase activation and cellular cholesterol efflux. J Clin Lipidol. 2015 May-Jun; 9(3):390-5. PMID: 26073399.
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    15. Rubin MR, Goldfine AB, McMahon DJ, Donovan DS, Cremers S, Dworakowski E, Schaefer EJ, Shoelson SE, Silverberg SJ. Effects of the anti-inflammatory drug salsalate on bone turnover in type 2 diabetes mellitus. Endocrine. 2015 Nov; 50(2):504-7. PMID: 25636441.
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    16. Asztalos BF, Horan MS, Horvath KV, McDermott AY, Chalasani NP, Schaefer EJ. Obesity associated molecular forms of C-reactive protein in human. PLoS One. 2014; 9(10):e109238. PMID: 25299074; PMCID: PMC4192316.
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    17. Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, Miller BL, Kane JP, Kwok PY, Malloy MJ. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. JAMA Neurol. 2014 Oct; 71(10):1228-36. PMID: 25111166.
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    18. Anthanont P, Polisecki E, Asztalos BF, Diffenderfer MR, Barrett PH, Millar JS, Billheimer J, Cuchel M, Rader DJ, Schaefer EJ. A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production. Atherosclerosis. 2014 Aug; 235(2):470-6. PMID: 24950002.
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    19. Schaefer EJ. Editorial introduction. Curr Opin Lipidol. 2014 Jun; 25(3):159-60. PMID: 24785963.
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    20. Schaefer EJ, Anthanont P, Asztalos BF. High-density lipoprotein metabolism, composition, function, and deficiency. Curr Opin Lipidol. 2014 Jun; 25(3):194-9. PMID: 24785961.
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    21. Diffenderfer MR, Schaefer EJ. The composition and metabolism of large and small LDL. Curr Opin Lipidol. 2014 Jun; 25(3):221-6. PMID: 24811298.
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    22. Akao H, Polisecki E, Schaefer EJ, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Packard C, Buckley BM, Kajinami K. ABCA1 gene variation and heart disease risk reduction in the elderly during pravastatin treatment. Atherosclerosis. 2014 Jul; 235(1):176-81. PMID: 24854628.
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    23. Mangili OC, Moron Gagliardi AC, Mangili LC, Mesquita CH, Machado Cesar LA, Tanaka A, Schaefer EJ, Maranhão RC, Santos RD. Favorable effects of ezetimibe alone or in association with simvastatin on the removal from plasma of chylomicrons in coronary heart disease subjects. Atherosclerosis. 2014 Mar; 233(1):319-25. PMID: 24503114.
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    24. Nakajima K, Nagamine T, Fujita MQ, Ai M, Tanaka A, Schaefer E. Apolipoprotein B-48: a unique marker of chylomicron metabolism. Adv Clin Chem. 2014; 64:117-77. PMID: 24938018.
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    25. Tani M, Matera R, Horvath KV, Hasan TS, Schaefer EJ, Asztalos BF. The influence of apoE-deficiency and LDL-receptor-deficiency on the HDL subpopulation profile in mice and in humans. Atherosclerosis. 2014 Mar; 233(1):39-44. PMID: 24529120.
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    26. Dimick SM, Sallee B, Asztalos BF, Pritchard PH, Frohlich J, Schaefer EJ. A kindred with fish eye disease, corneal opacities, marked high-density lipoprotein deficiency, and statin therapy. J Clin Lipidol. 2014 Mar-Apr; 8(2):223-30. PMID: 24636183.
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    27. Voros S, Joshi P, Qian Z, Rinehart S, Vazquez-Figueroa JG, Anderson H, Elashoff M, Murrieta L, Karmpaliotis D, Kalynych A, Brown C, Schaefer E, Asztalos B. Apoprotein B, small-dense LDL and impaired HDL remodeling is associated with larger plaque burden and more noncalcified plaque as assessed by coronary CT angiography and intravascular ultrasound with radiofrequency backscatter: results from the ATLANTA I study. J Am Heart Assoc. 2013; 2(6):e000344. PMID: 24252842; PMCID: PMC3886774.
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    28. Furusyo N, Ai M, Okazaki M, Ikezaki H, Ihara T, Hayashi T, Hiramine S, Ura K, Kohzuma T, Schaefer EJ, Hayashi J. Serum cholesterol and triglyceride reference ranges of twenty lipoprotein subclasses for healthy Japanese men and women. Atherosclerosis. 2013 Dec; 231(2):238-45. PMID: 24267234.
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    29. Connolly BA, O'Connell DP, Lamon-Fava S, LeBlanc DF, Kuang YL, Schaefer EJ, Coppage AL, Benedict CR, Kiritsy CP, Bachovchin WW. The high-fat high-fructose hamster as an animal model for niacin's biological activities in humans. Metabolism. 2013 Dec; 62(12):1840-9. PMID: 24035454.
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    30. Yatsuzuka S, Shimomura Y, Akuzawa M, Ando Y, Kobayashi I, Nakano T, Tokita Y, Nagamine T, Ono H, Tanaka A, Schaefer E, Nakajima K. Plasma adiponectin is a more specific marker of fatty liver than a marker of metabolic syndrome in Japanese men. Ann Clin Biochem. 2014 Jan; 51(Pt 1):68-79. PMID: 23897104.
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    31. Schaefer E, Lauer J, Durand M, Pelletier V, Obringer C, Claussmann A, Braun JJ, Redin C, Mathis C, Muller J, Schmidt-Mutter C, Flori E, Marion V, Stoetzel C, Dollfus H. Mesoaxial polydactyly is a major feature in Bardet-Biedl syndrome patients with LZTFL1 (BBS17) mutations. Clin Genet. 2014 May; 85(5):476-81. PMID: 23692385.
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    32. Schaefer EJ. Editorial introduction. Human lipoprotein metabolism and therapeutic options for coronary heart disease (CHD) reduction. Curr Opin Lipidol. 2013 Jun; 24(3):191. PMID: 23652566.
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    33. Schaefer EJ. Effects of cholesteryl ester transfer protein inhibitors on human lipoprotein metabolism: why have they failed in lowering coronary heart disease risk? Curr Opin Lipidol. 2013 Jun; 24(3):259-64. PMID: 23652567.
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    34. Matthan NR, Zhu L, Pencina M, D'Agostino RB, Schaefer EJ, Lichtenstein AH. Sex-specific differences in the predictive value of cholesterol homeostasis markers and 10-year cardiovascular disease event rate in Framingham Offspring Study participants. J Am Heart Assoc. 2013 Feb; 2(1):e005066. PMID: 23525441; PMCID: PMC3603247.
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    35. Gaudineau A, Doray B, Schaefer E, Sananès N, Fritz G, Kohler M, Alembik Y, Viville B, Favre R, Langer B. Postnatal phenotype according to prenatal ultrasound features of Noonan syndrome: a retrospective study of 28 cases. Prenat Diagn. 2013 Mar; 33(3):238-41. PMID: 23345196.
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    36. Brouwers MC, Konrad RJ, van Himbergen TM, Isaacs A, Otokozawa S, Troutt JS, Schaefer EJ, van Greevenbroek MM, Stalenhoef AF, de Graaf J. Plasma proprotein convertase subtilisin kexin type 9 levels are related to markers of cholesterol synthesis in familial combined hyperlipidemia. Nutr Metab Cardiovasc Dis. 2013 Nov; 23(11):1115-21. PMID: 23333725.
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    37. Thongtang N, Diffenderfer MR, Ooi EM, Asztalos BF, Dolnikowski GG, Lamon-Fava S, Schaefer EJ. Effects of atorvastatin on human C-reactive protein metabolism. Atherosclerosis. 2013 Feb; 226(2):466-70. PMID: 23218801.
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    38. Lee EY, Klementowicz PT, Hegele RA, Asztalos BF, Schaefer EJ. HDL deficiency due to a new insertion mutation (ApoA-INashua) and review of the literature. J Clin Lipidol. 2013 Mar-Apr; 7(2):169-73. PMID: 23415437.
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    39. Negi SI, Brautbar A, Virani SS, Anand A, Polisecki E, Asztalos BF, Ballantyne CM, Schaefer EJ, Jones PH. A novel mutation in the ABCA1 gene causing an atypical phenotype of Tangier disease. J Clin Lipidol. 2013 Jan-Feb; 7(1):82-7. PMID: 23351586.
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    40. Thongtang N, Diffenderfer MR, Ooi EM, Asztalos BF, Dolnikowski GG, Lamon-Fava S, Schaefer EJ. Linkage between C-reactive protein and triglyceride-rich lipoprotein metabolism. Metabolism. 2013 Mar; 62(3):369-75. PMID: 23018145.
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    41. Thongtang N, Lin J, Schaefer EJ, Lowe RS, Tomassini JE, Shah AK, Tershakovec AM. Effects of ezetimibe added to statin therapy on markers of cholesterol absorption and synthesis and LDL-C lowering in hyperlipidemic patients. Atherosclerosis. 2012 Dec; 225(2):388-96. PMID: 23040830; NIHMSID: NIHMS493752.
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    42. Sever S, Weinstein DA, Wolfsdorf JI, Gedik R, Schaefer EJ. Glycogen storage disease type Ia: linkage of glucose, glycogen, lactic acid, triglyceride, and uric acid metabolism. J Clin Lipidol. 2012 Nov-Dec; 6(6):596-600. PMID: 23312056; NIHMSID: NIHMS490718.
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    43. Ooi EM, Lichtenstein AH, Millar JS, Diffenderfer MR, Lamon-Fava S, Rasmussen H, Welty FK, Barrett PH, Schaefer EJ. Effects of Therapeutic Lifestyle Change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects. J Lipid Res. 2012 Sep; 53(9):1958-67. PMID: 22773687; PMCID: PMC3413235.
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    44. Furusyo N, Koga T, Ai M, Otokozawa S, Kohzuma T, Ikezaki H, Schaefer EJ, Hayashi J. Plasma glycated albumin level and atherosclerosis: results from the Kyushu and Okinawa Population Study (KOPS). Int J Cardiol. 2013 Sep 1; 167(5):2066-72. PMID: 22658569.
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    45. Farina EK, Kiel DP, Roubenoff R, Schaefer EJ, Cupples LA, Tucker KL. Plasma phosphatidylcholine concentrations of polyunsaturated fatty acids are differentially associated with hip bone mineral density and hip fracture in older adults: the Framingham Osteoporosis Study. J Bone Miner Res. 2012 May; 27(5):1222-30. PMID: 22392875; NIHMSID: NIHMS433061.
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    46. van Himbergen TM, Beiser AS, Ai M, Seshadri S, Otokozawa S, Au R, Thongtang N, Wolf PA, Schaefer EJ. Biomarkers for insulin resistance and inflammation and the risk for all-cause dementia and alzheimer disease: results from the Framingham Heart Study. Arch Neurol. 2012 May; 69(5):594-600. PMID: 22213409; NIHMSID: NIHMS421674.
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    47. Diffenderfer MR, Brousseau ME, Millar JS, Barrett PH, Nartsupha C, Schaefer PM, Wolfe ML, Dolnikowski GG, Rader DJ, Schaefer EJ. Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism. J Lipid Res. 2012 Jun; 53(6):1190-9. PMID: 22474066; PMCID: PMC3351826.
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    48. Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ. KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly. Atherosclerosis. 2012 Feb; 220(2):456-62. PMID: 22192511.
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    49. Ooi EM, Russell BS, Olson E, Sun SZ, Diffenderfer MR, Lichtenstein AH, Keilson L, Barrett PH, Schaefer EJ, Sprecher DL. Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):459-66. PMID: 22095987.
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    50. Furusyo N, Koga T, Ai M, Otokozawa S, Kohzuma T, Ikezaki H, Schaefer EJ, Hayashi J. Utility of glycated albumin for the diagnosis of diabetes mellitus in a Japanese population study: results from the Kyushu and Okinawa Population Study (KOPS). Diabetologia. 2011 Dec; 54(12):3028-36. PMID: 21947435.
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    51. Akao H, Polisecki E, Kajinami K, Trompet S, Robertson M, Ford I, Jukema JW, de Craen AJ, Westendorp RG, Shepherd J, Packard C, Buckley BM, Schaefer EJ. Genetic variation at the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly. Atherosclerosis. 2012 Feb; 220(2):413-7. PMID: 22189199.
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    52. Mooijaart SP, Sattar N, Trompet S, Polisecki E, de Craen AJ, Schaefer EJ, Jahn SE, van Himbergen T, Welsh P, Ford I, Stott DJ, Westendorp RG. C-reactive protein and genetic variants and cognitive decline in old age: the PROSPER study. PLoS One. 2011; 6(9):e23890. PMID: 21915265; PMCID: PMC3168438.
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    53. Roshan B, Ganda OP, Desilva R, Ganim RB, Ward E, Haessler SD, Polisecki EY, Asztalos BF, Schaefer EJ. Homozygous lecithin:cholesterol acyltransferase (LCAT) deficiency due to a new loss of function mutation and review of the literature. J Clin Lipidol. 2011 Nov-Dec; 5(6):493-9. PMID: 22108153.
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    54. Varlotto J, Medford-Davis LN, Recht A, Flickinger J, Schaefer E, Shelkey J, Lazar M, Campbell D, Nikolov M, Decamp MM. Confirmation of the role of diabetes in the local recurrence of surgically resected non-small cell lung cancer. Lung Cancer. 2012 Mar; 75(3):381-90. PMID: 21864933.
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    55. Corcoran MP, Lichtenstein AH, Meydani M, Dillard A, Schaefer EJ, Lamon-Fava S. The effect of 17ß-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu. J Mol Endocrinol. 2011 Aug; 47(1):109-117. PMID: 21830321; NIHMSID: NIHMS319068.
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    56. Ai M, Otokozawa S, Asztalos BF, White CC, Cupples LA, Nakajima K, Lamon-Fava S, Wilson PW, Matsuzawa Y, Schaefer EJ. Adiponectin: an independent risk factor for coronary heart disease in men in the Framingham offspring Study. Atherosclerosis. 2011 Aug; 217(2):543-8. PMID: 21741045; NIHMSID: NIHMS351960.
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    57. Asztalos BF, Tani M, Schaefer EJ. Metabolic and functional relevance of HDL subspecies. Curr Opin Lipidol. 2011 Jun; 22(3):176-85. PMID: 21537175.
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    58. Stanhope KL, Griffen SC, Bremer AA, Vink RG, Schaefer EJ, Nakajima K, Schwarz JM, Beysen C, Berglund L, Keim NL, Havel PJ. Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions. Am J Clin Nutr. 2011 Jul; 94(1):112-9. PMID: 21613559; PMCID: PMC3127512.
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    59. Farina EK, Kiel DP, Roubenoff R, Schaefer EJ, Cupples LA, Tucker KL. Dietary intakes of arachidonic acid and alpha-linolenic acid are associated with reduced risk of hip fracture in older adults. J Nutr. 2011 Jun; 141(6):1146-53. PMID: 21508210; PMCID: PMC3095142.
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    60. Lamon-Fava S, Marcovina SM, Albers JJ, Kennedy H, Deluca C, White CC, Cupples LA, McNamara JR, Seman LJ, Bongard V, Schaefer EJ. Lipoprotein(a) levels, apo(a) isoform size, and coronary heart disease risk in the Framingham Offspring Study. J Lipid Res. 2011 Jun; 52(6):1181-7. PMID: 21478162; PMCID: PMC3090239.
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    61. Sun JK, Keenan HA, Cavallerano JD, Asztalos BF, Schaefer EJ, Sell DR, Strauch CM, Monnier VM, Doria A, Aiello LP, King GL. Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study. Diabetes Care. 2011 Apr; 34(4):968-74. PMID: 21447665; PMCID: PMC3064059.
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    62. Schaefer EJ, Otokozawa S, Ai M. Limitations of direct methods and the reference method for measuring HDL and LDL cholesterol. Clin Chem. 2011 Jul; 57(7):1081-3; author reply 1083. PMID: 21444737.
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    63. Farina EK, Kiel DP, Roubenoff R, Schaefer EJ, Cupples LA, Tucker KL. Protective effects of fish intake and interactive effects of long-chain polyunsaturated fatty acid intakes on hip bone mineral density in older adults: the Framingham Osteoporosis Study. Am J Clin Nutr. 2011 May; 93(5):1142-51. PMID: 21367955; PMCID: PMC3076660.
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    64. Ge Z, Yuan Y, Zhang S, Hou X, Wang J, Cai J, Shi R, Li Y, Wang B, Ji F, Richter E, Schaefer E. Efficacy and tolerability of two oral hyoscine butylbromide formulations in Chinese patients with recurrent episodes of self-reported gastric or intestinal spasm-like pain. Int J Clin Pharmacol Ther. 2011 Mar; 49(3):198-205. PMID: 21329622.
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    65. Thongtang N, Ai M, Otokozawa S, Himbergen TV, Asztalos BF, Nakajima K, Stein E, Jones PH, Schaefer EJ. Effects of maximal atorvastatin and rosuvastatin treatment on markers of glucose homeostasis and inflammation. Am J Cardiol. 2011 Feb 1; 107(3):387-92. PMID: 21257003.
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    66. Rosenson RS, Brewer HB, Chapman MJ, Fazio S, Hussain MM, Kontush A, Krauss RM, Otvos JD, Remaley AT, Schaefer EJ. HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events. Clin Chem. 2011 Mar; 57(3):392-410. PMID: 21266551.
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    67. Peloso GM, Demissie S, Collins D, Mirel DB, Gabriel SB, Cupples LA, Robins SJ, Schaefer EJ, Brousseau ME. Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease. J Lipid Res. 2010 Dec; 51(12):3524-32. PMID: 20855565; PMCID: PMC2975725.
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    68. Schaefer EJ, Santos RD, Asztalos BF. Marked HDL deficiency and premature coronary heart disease. Curr Opin Lipidol. 2010 Aug; 21(4):289-97. PMID: 20616715.
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    69. Asztalos BF, Swarbrick MM, Schaefer EJ, Dallal GE, Horvath KV, Ai M, Stanhope KL, Austrheim-Smith I, Wolfe BM, Ali M, Havel PJ. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women. J Lipid Res. 2010 Aug; 51(8):2405-12. PMID: 20631298; PMCID: PMC2903819.
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    70. Gagliardi AC, Maranhão RC, de Sousa HP, Schaefer EJ, Santos RD. Effects of margarines and butter consumption on lipid profiles, inflammation markers and lipid transfer to HDL particles in free-living subjects with the metabolic syndrome. Eur J Clin Nutr. 2010 Oct; 64(10):1141-9. PMID: 20648041.
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    71. Lamon-Fava S, Herrington DM, Horvath KV, Schaefer EJ, Asztalos BF. Effect of hormone replacement therapy on plasma lipoprotein levels and coronary atherosclerosis progression in postmenopausal women according to type 2 diabetes mellitus status. Metabolism. 2010 Dec; 59(12):1794-800. PMID: 20580029; NIHMSID: NIHMS209706.
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    72. Burgess S, Thompson SG. Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables. Stat Med. 2010 May 30; 29(12):1298-311. PMID: 20209660; NIHMSID: NIHMS459889.
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    73. Mueller-Lissner S, Quigley EM, Helfrich I, Schaefer E. Drug treatment of chronic-intermittent abdominal cramping and pain: a multi-national survey on usage and attitudes. Aliment Pharmacol Ther. 2010 Aug; 32(3):472-7. PMID: 20497145.
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    74. Corcoran MP, Meydani M, Lichtenstein AH, Schaefer EJ, Dillard A, Lamon-Fava S. Sex hormone modulation of proinflammatory cytokine and C-reactive protein expression in macrophages from older men and postmenopausal women. J Endocrinol. 2010 Aug; 206(2):217-24. PMID: 20484148; NIHMSID: NIHMS235418.
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    75. Ai M, Otokozawa S, Asztalos BF, Ito Y, Nakajima K, White CC, Cupples LA, Wilson PW, Schaefer EJ. Small dense LDL cholesterol and coronary heart disease: results from the Framingham Offspring Study. Clin Chem. 2010 Jun; 56(6):967-76. PMID: 20431054; NIHMSID: NIHMS476458.
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    76. Berson EL, Rosner B, Sandberg MA, Weigel-DiFranco C, Brockhurst RJ, Hayes KC, Johnson EJ, Anderson EJ, Johnson CA, Gaudio AR, Willett WC, Schaefer EJ. Clinical trial of lutein in patients with retinitis pigmentosa receiving vitamin A. Arch Ophthalmol. 2010 Apr; 128(4):403-11. PMID: 20385935; NIHMSID: NIHMS237521.
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    77. Otokozawa S, Ai M, Asztalos BF, White CC, Demissie-Banjaw S, Cupples LA, Nakajima K, Wilson PW, Schaefer EJ. Direct assessment of plasma low density lipoprotein and high density lipoprotein cholesterol levels and coronary heart disease: results from the Framingham Offspring Study. Atherosclerosis. 2010 Nov; 213(1):251-5. PMID: 20863498; NIHMSID: NIHMS472524.
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    78. Schaefer EJ. Northern light: a commentary on the 2009 Canadian Guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in adults. Clin Chem. 2010 Apr; 56(4):502-4. PMID: 20185622.
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    87. Lamon-Fava S, Asztalos BF, Howard TD, Reboussin DM, Horvath KV, Schaefer EJ, Herrington DM. Association of polymorphisms in genes involved in lipoprotein metabolism with plasma concentrations of remnant lipoproteins and HDL subpopulations before and after hormone therapy in postmenopausal women. Clin Endocrinol (Oxf). 2010 Feb; 72(2):169-75. PMID: 19489872; NIHMSID: NIHMS139981.
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    89. Ewig S, Birkner N, Strauss R, Schaefer E, Pauletzki J, Bischoff H, Schraeder P, Welte T, Hoeffken G. New perspectives on community-acquired pneumonia in 388 406 patients. Results from a nationwide mandatory performance measurement programme in healthcare quality. Thorax. 2009 Dec; 64(12):1062-9. PMID: 19454409; PMCID: PMC2782114.
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    90. Matthan NR, Pencina M, LaRocque JM, Jacques PF, D'Agostino RB, Schaefer EJ, Lichtenstein AH. Alterations in cholesterol absorption/synthesis markers characterize Framingham offspring study participants with CHD. J Lipid Res. 2009 Sep; 50(9):1927-35. PMID: 19436064; PMCID: PMC2724787.
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    91. Schaefer EJ, Gleason JA, Dansinger ML. Dietary fructose and glucose differentially affect lipid and glucose homeostasis. J Nutr. 2009 Jun; 139(6):1257S-1262S. PMID: 19403705; PMCID: PMC2682989.
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    92. Wada M, Iso T, Asztalos BF, Takama N, Nakajima T, Seta Y, Kaneko K, Taniguchi Y, Kobayashi H, Nakajima K, Schaefer EJ, Kurabayashi M. Marked high density lipoprotein deficiency due to apolipoprotein A-I Tomioka (codon 138 deletion). Atherosclerosis. 2009 Nov; 207(1):157-61. PMID: 19473658.
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    93. Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest. 2009 May; 119(5):1322-34. PMID: 19381015; PMCID: PMC2673878.
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    94. Vega-López S, Matthan NR, Ausman LM, Ai M, Otokozawa S, Schaefer EJ, Lichtenstein AH. Substitution of vegetable oil for a partially-hydrogenated fat favorably alters cardiovascular disease risk factors in moderately hypercholesterolemic postmenopausal women. Atherosclerosis. 2009 Nov; 207(1):208-12. PMID: 19423109; NIHMSID: NIHMS217857.
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    97. Sanchez-Muniz FJ, Maki KC, Schaefer EJ, Ordovas JM. Serum lipid and antioxidant responses in hypercholesterolemic men and women receiving plant sterol esters vary by apolipoprotein E genotype. J Nutr. 2009 Jan; 139(1):13-9. PMID: 19056656.
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    98. van Himbergen TM, Matthan NR, Resteghini NA, Otokozawa S, Ai M, Stein EA, Jones PH, Schaefer EJ. Comparison of the effects of maximal dose atorvastatin and rosuvastatin therapy on cholesterol synthesis and absorption markers. J Lipid Res. 2009 Apr; 50(4):730-9. PMID: 19043140; PMCID: PMC2656667.
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    103. Santos RD, Asztalos BF, Martinez LR, Miname MH, Polisecki E, Schaefer EJ. Clinical presentation, laboratory values, and coronary heart disease risk in marked high-density lipoprotein-deficiency states. J Clin Lipidol. 2008 Aug; 2(4):237-47. PMID: 21291740.
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    104. Miller M, Ginsberg HN, Schaefer EJ. Relative atherogenicity and predictive value of non-high-density lipoprotein cholesterol for coronary heart disease. Am J Cardiol. 2008 Apr 1; 101(7):1003-8. PMID: 18359322.
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    105. Polisecki E, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ. Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population. Atherosclerosis. 2008 Sep; 200(1):95-101. PMID: 18262190.
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    107. Lamon-Fava S, Herrington DM, Reboussin DM, Sherman M, Horvath KV, Cupples LA, White C, Demissie S, Schaefer EJ, Asztalos BF. Plasma levels of HDL subpopulations and remnant lipoproteins predict the extent of angiographically-defined coronary artery disease in postmenopausal women. Arterioscler Thromb Vasc Biol. 2008 Mar; 28(3):575-9. PMID: 18174456.
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    108. Asztalos BF, Collins D, Horvath KV, Bloomfield HE, Robins SJ, Schaefer EJ. Relation of gemfibrozil treatment and high-density lipoprotein subpopulation profile with cardiovascular events in the Veterans Affairs High-Density Lipoprotein Intervention Trial. Metabolism. 2008 Jan; 57(1):77-83. PMID: 18078862; NIHMSID: NIHMS36505.
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    109. Harris WS, Miller M, Tighe AP, Davidson MH, Schaefer EJ. Omega-3 fatty acids and coronary heart disease risk: clinical and mechanistic perspectives. Atherosclerosis. 2008 Mar; 197(1):12-24. PMID: 18160071.
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    110. Ai M, Otokozawa S, Asztalos BF, Nakajima K, Stein E, Jones PH, Schaefer EJ. Effects of maximal doses of atorvastatin versus rosuvastatin on small dense low-density lipoprotein cholesterol levels. Am J Cardiol. 2008 Feb 1; 101(3):315-8. PMID: 18237592.
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    112. Millar JS, Brousseau ME, Diffenderfer MR, Barrett PH, Welty FK, Cohn JS, Wilson A, Wolfe ML, Nartsupha C, Schaefer PM, Digenio AG, Mancuso JP, Dolnikowski GG, Schaefer EJ, Rader DJ. Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism. J Lipid Res. 2008 Mar; 49(3):543-9. PMID: 18033754.
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    113. Santos RD, Schaefer EJ, Asztalos BF, Polisecki E, Wang J, Hegele RA, Martinez LR, Miname MH, Rochitte CE, Da Luz PL, Maranhão RC. Characterization of high density lipoprotein particles in familial apolipoprotein A-I deficiency. J Lipid Res. 2008 Feb; 49(2):349-57. PMID: 17991756.
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    114. Santos RD, Miname MH, Martinez LR, Rochitte CE, Chacra AP, Nakandakare ER, Chen D, Schaefer EJ. Non-invasive detection of aortic and coronary atherosclerosis in homozygous familial hypercholesterolemia by 64 slice multi-detector row computed tomography angiography. Atherosclerosis. 2008 Apr; 197(2):910-5. PMID: 17884061.
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    118. Bongard V, McDermott AY, Dallal GE, Schaefer EJ. Effects of age and gender on physical performance. Age (Dordr). 2007 Sep; 29(2-3):77-85. PMID: 19424833; PMCID: PMC2267663.
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    120. Jacobson TA, Miller M, Schaefer EJ. Hypertriglyceridemia and cardiovascular risk reduction. Clin Ther. 2007 May; 29(5):763-77. PMID: 17697898.
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    121. Friso S, Lamon-Fava S, Jang H, Schaefer EJ, Corrocher R, Choi SW. Oestrogen replacement therapy reduces total plasma homocysteine and enhances genomic DNA methylation in postmenopausal women. Br J Nutr. 2007 Apr; 97(4):617-21. PMID: 17349072.
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    122. Asztalos BF, Le Maulf F, Dallal GE, Stein E, Jones PH, Horvath KV, McTaggart F, Schaefer EJ. Comparison of the effects of high doses of rosuvastatin versus atorvastatin on the subpopulations of high-density lipoproteins. Am J Cardiol. 2007 Mar 1; 99(5):681-5. PMID: 17317371.
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    123. Asztalos BF, Schaefer EJ, Horvath KV, Yamashita S, Miller M, Franceschini G, Calabresi L. Role of LCAT in HDL remodeling: investigation of LCAT deficiency states. J Lipid Res. 2007 Mar; 48(3):592-9. PMID: 17183024.
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    125. Mangili A, Gerrior J, Tang AM, O'Leary DH, Polak JK, Schaefer EJ, Gorbach SL, Wanke CA. Risk of cardiovascular disease in a cohort of HIV-infected adults: a study using carotid intima-media thickness and coronary artery calcium score. Clin Infect Dis. 2006 Dec 1; 43(11):1482-9. PMID: 17083026.
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    126. Lichtenstein AH, Matthan NR, Jalbert SM, Resteghini NA, Schaefer EJ, Ausman LM. Novel soybean oils with different fatty acid profiles alter cardiovascular disease risk factors in moderately hyperlipidemic subjects. Am J Clin Nutr. 2006 Sep; 84(3):497-504. PMID: 16960162.
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    128. Quigley EM, Locke GR, Mueller-Lissner S, Paulo LG, Tytgat GN, Helfrich I, Schaefer E. Prevalence and management of abdominal cramping and pain: a multinational survey. Aliment Pharmacol Ther. 2006 Jul 15; 24(2):411-9. PMID: 16842469.
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    130. Johnson EJ, Schaefer EJ. Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degeneration. Am J Clin Nutr. 2006 Jun; 83(6 Suppl):1494S-1498S. PMID: 16841859.
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    131. Millar JS, Brousseau ME, Diffenderfer MR, Barrett PH, Welty FK, Faruqi A, Wolfe ML, Nartsupha C, Digenio AG, Mancuso JP, Dolnikowski GG, Schaefer EJ, Rader DJ. Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on apolipoprotein B100 metabolism in humans. Arterioscler Thromb Vasc Biol. 2006 Jun; 26(6):1350-6. PMID: 16574893.
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    132. Otvos JD, Collins D, Freedman DS, Shalaurova I, Schaefer EJ, McNamara JR, Bloomfield HE, Robins SJ. Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial. Circulation. 2006 Mar 28; 113(12):1556-63. PMID: 16534013.
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    133. Dansinger ML, Schaefer EJ. Low-carbohydrate or low-fat diets for the metabolic syndrome? Curr Diab Rep. 2006 Feb; 6(1):55-63. PMID: 16522282.
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    134. Dansinger ML, Schaefer EJ. Low-fat diets and weight change. JAMA. 2006 Jan 4; 295(1):94-5. PMID: 16391222.
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    135. Schaefer EJ, Asztalos BF. The effects of statins on high-density lipoproteins. Curr Atheroscler Rep. 2006 Jan; 8(1):41-9. PMID: 16455013.
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    136. Kathiresan S, Otvos JD, Sullivan LM, Keyes MJ, Schaefer EJ, Wilson PW, D'Agostino RB, Vasan RS, Robins SJ. Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study. Circulation. 2006 Jan 3; 113(1):20-9. PMID: 16380547.
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    137. Lamon-Fava S, Postfai B, Diffenderfer M, DeLuca C, O'Connor J, Welty FK, Dolnikowski GG, Barrett PH, Schaefer EJ. Role of the estrogen and progestin in hormonal replacement therapy on apolipoprotein A-I kinetics in postmenopausal women. Arterioscler Thromb Vasc Biol. 2006 Feb; 26(2):385-91. PMID: 16339502; NIHMSID: NIHMS332627.
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    138. Kajinami K, Okabayashi M, Sato R, Polisecki E, Schaefer EJ. Statin pharmacogenomics: what have we learned, and what remains unanswered? Curr Opin Lipidol. 2005 Dec; 16(6):606-13. PMID: 16276236.
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    139. Asztalos BF, Demissie S, Cupples LA, Collins D, Cox CE, Horvath KV, Bloomfield HE, Robins SJ, Schaefer EJ. LpA-I, LpA-I:A-II HDL and CHD-risk: The Framingham Offspring Study and the Veterans Affairs HDL Intervention Trial. Atherosclerosis. 2006 Sep; 188(1):59-67. PMID: 16298372.
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    140. Schaefer EJ, Gleason JA, Dansinger ML. The effects of low-fat, high-carbohydrate diets on plasma lipoproteins, weight loss, and heart disease risk reduction. Curr Atheroscler Rep. 2005 Nov; 7(6):421-7. PMID: 16255999.
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    142. Tai ES, Collins D, Robins SJ, O'Connor JJ, Bloomfield HE, Ordovas JM, Schaefer EJ, Brousseau ME. The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT). Atherosclerosis. 2006 Jul; 187(1):153-60. PMID: 16221474.
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    143. Chiesa R, Marone EM, Limoni C, Volonté M, Schaefer E, Petrini O. Chronic venous insufficiency in Italy: the 24-cities cohort study. Eur J Vasc Endovasc Surg. 2005 Oct; 30(4):422-9. PMID: 16009576.
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    145. Asztalos BF, de la Llera-Moya M, Dallal GE, Horvath KV, Schaefer EJ, Rothblat GH. Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux. J Lipid Res. 2005 Oct; 46(10):2246-53. PMID: 16061948.
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    147. Kajinami K, Masuya H, Hoshiba Y, Takeda K, Sato R, Okabayashi M, Schaefer EJ. Statin response and pharmacokinetics variants. Expert Opin Pharmacother. 2005 Jul; 6(8):1291-7. PMID: 16013979.
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    148. Matthan NR, Jalbert SM, Lamon-Fava S, Dolnikowski GG, Welty FK, Barrett HR, Schaefer EJ, Lichtenstein AH. TRL, IDL, and LDL apolipoprotein B-100 and HDL apolipoprotein A-I kinetics as a function of age and menopausal status. Arterioscler Thromb Vasc Biol. 2005 Aug; 25(8):1691-6. PMID: 15933247.
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    149. Asztalos BF, Schaefer EJ, Horvath KV, Cox CE, Skinner S, Gerrior J, Gorbach SL, Wanke C. Protease inhibitor-based HAART, HDL, and CHD-risk in HIV-infected patients. Atherosclerosis. 2006 Jan; 184(1):72-7. PMID: 15935358.
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    150. Kajinami K, Brousseau ME, Ordovas JM, Schaefer EJ. A promoter polymorphism in cholesterol 7alpha-hydroxylase interacts with apolipoprotein E genotype in the LDL-lowering response to atorvastatin. Atherosclerosis. 2005 Jun; 180(2):407-15. PMID: 15910869.
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    151. Lamon-Fava S, Barnett JB, Woods MN, McCormack C, McNamara JR, Schaefer EJ, Longcope C, Rosner B, Gorbach SL. Differences in serum sex hormone and plasma lipid levels in Caucasian and African-American premenopausal women. J Clin Endocrinol Metab. 2005 Aug; 90(8):4516-20. PMID: 15886254.
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    152. Schaefer EJ, McNamara JR, Asztalos BF, Tayler T, Daly JA, Gleason JL, Seman LJ, Ferrari A, Rubenstein JJ. Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects. Am J Cardiol. 2005 May 1; 95(9):1025-32. PMID: 15842965.
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    153. Brousseau ME, Diffenderfer MR, Millar JS, Nartsupha C, Asztalos BF, Welty FK, Wolfe ML, Rudling M, Björkhem I, Angelin B, Mancuso JP, Digenio AG, Rader DJ, Schaefer EJ. Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion. Arterioscler Thromb Vasc Biol. 2005 May; 25(5):1057-64. PMID: 15761191; NIHMSID: NIHMS332629.
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    154. Schaefer E, Mehta A, Gal A. Genotype and phenotype in Fabry disease: analysis of the Fabry Outcome Survey. Acta Paediatr Suppl. 2005 Mar; 94(447):87-92; discussion 79. PMID: 15895718.
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    155. Jenner JL, Seman LJ, Millar JS, Lamon-Fava S, Welty FK, Dolnikowski GG, Marcovina SM, Lichtenstein AH, Barrett PH, deLuca C, Schaefer EJ. The metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein (a) in human beings. Metabolism. 2005 Mar; 54(3):361-9. PMID: 15736114.
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    156. Tai ES, Corella D, Demissie S, Cupples LA, Coltell O, Schaefer EJ, Tucker KL, Ordovas JM. Polyunsaturated fatty acids interact with the PPARA-L162V polymorphism to affect plasma triglyceride and apolipoprotein C-III concentrations in the Framingham Heart Study. J Nutr. 2005 Mar; 135(3):397-403. PMID: 15735069.
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    157. Kajinami K, Brousseau ME, Lamon-Fava S, Ordovas JM, Schaefer EJ. Gender-specific effects of estrogen receptor alpha gene haplotype on high-density lipoprotein cholesterol response to atorvastatin: interaction with apolipoprotein AI gene polymorphism. Atherosclerosis. 2005 Feb; 178(2):331-8. PMID: 15694942.
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    158. Dansinger ML, Gleason JA, Griffith JL, Selker HP, Schaefer EJ. Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial. JAMA. 2005 Jan 5; 293(1):43-53. PMID: 15632335.
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    161. Qi L, Shen H, Larson I, Schaefer EJ, Greenberg AS, Tregouet DA, Corella D, Ordovas JM. Gender-specific association of a perilipin gene haplotype with obesity risk in a white population. Obes Res. 2004 Nov; 12(11):1758-65. PMID: 15601970.
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    164. Berson EL, Rosner B, Sandberg MA, Weigel-DiFranco C, Moser A, Brockhurst RJ, Hayes KC, Johnson CA, Anderson EJ, Gaudio AR, Willett WC, Schaefer EJ. Clinical trial of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment. Arch Ophthalmol. 2004 Sep; 122(9):1297-305. PMID: 15364708.
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    165. Berson EL, Rosner B, Sandberg MA, Weigel-DiFranco C, Moser A, Brockhurst RJ, Hayes KC, Johnson CA, Anderson EJ, Gaudio AR, Willett WC, Schaefer EJ. Further evaluation of docosahexaenoic acid in patients with retinitis pigmentosa receiving vitamin A treatment: subgroup analyses. Arch Ophthalmol. 2004 Sep; 122(9):1306-14. PMID: 15364709.
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    166. Brousseau ME, Goldkamp AL, Collins D, Demissie S, Connolly AC, Cupples LA, Ordovas JM, Bloomfield HE, Robins SJ, Schaefer EJ. Polymorphisms in the gene encoding lipoprotein lipase in men with low HDL-C and coronary heart disease: the Veterans Affairs HDL Intervention Trial. J Lipid Res. 2004 Oct; 45(10):1885-91. PMID: 15292370.
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    167. Kajinami K, Brousseau ME, Ordovas JM, Schaefer EJ. Interactions between common genetic polymorphisms in ABCG5/G8 and CYP7A1 on LDL cholesterol-lowering response to atorvastatin. Atherosclerosis. 2004 Aug; 175(2):287-93. PMID: 15262185.
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    169. Li Z, Lamon-Fava S, Otvos J, Lichtenstein AH, Velez-Carrasco W, McNamara JR, Ordovas JM, Schaefer EJ. Fish consumption shifts lipoprotein subfractions to a less atherogenic pattern in humans. J Nutr. 2004 Jul; 134(7):1724-8. PMID: 15226460.
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    170. Freedman DS, Otvos JD, Jeyarajah EJ, Shalaurova I, Cupples LA, Parise H, D'Agostino RB, Wilson PW, Schaefer EJ. Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study. Clin Chem. 2004 Jul; 50(7):1189-200. PMID: 15107310.
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    171. Matthan NR, Welty FK, Barrett PH, Harausz C, Dolnikowski GG, Parks JS, Eckel RH, Schaefer EJ, Lichtenstein AH. Dietary hydrogenated fat increases high-density lipoprotein apoA-I catabolism and decreases low-density lipoprotein apoB-100 catabolism in hypercholesterolemic women. Arterioscler Thromb Vasc Biol. 2004 Jun; 24(6):1092-7. PMID: 15087307.
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    173. Brousseau ME, Schaefer EJ, Wolfe ML, Bloedon LT, Digenio AG, Clark RW, Mancuso JP, Rader DJ. Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol. N Engl J Med. 2004 Apr 8; 350(15):1505-15. PMID: 15071125.
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    174. Tilly-Kiesi M, Schaefer EJ, Knudsen P, Welty FK, Dolnikowski GG, Taskinen MR, Lichtenstein AH. Lipoprotein metabolism in subjects with hepatic lipase deficiency. Metabolism. 2004 Apr; 53(4):520-5. PMID: 15045702.
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    175. Barnett JB, Woods MN, Lamon-Fava S, Schaefer EJ, McNamara JR, Spiegelman D, Hertzmark E, Goldin B, Longcope C, Gorbach SL. Plasma lipid and lipoprotein levels during the follicular and luteal phases of the menstrual cycle. J Clin Endocrinol Metab. 2004 Feb; 89(2):776-82. PMID: 14764796.
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    176. Qi L, Shen H, Larson I, Barnard JR, Schaefer EJ, Ordovas JM. Genetic variation at the hormone sensitive lipase: gender-specific association with plasma lipid and glucose concentrations. Clin Genet. 2004 Feb; 65(2):93-100. PMID: 14984467.
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    177. Schaefer EJ, McNamara JR, Tayler T, Daly JA, Gleason JL, Seman LJ, Ferrari A, Rubenstein JJ. Comparisons of effects of statins (atorvastatin, fluvastatin, lovastatin, pravastatin, and simvastatin) on fasting and postprandial lipoproteins in patients with coronary heart disease versus control subjects. Am J Cardiol. 2004 Jan 1; 93(1):31-9. PMID: 14697462.
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    178. Kajinami K, Brousseau ME, Nartsupha C, Ordovas JM, Schaefer EJ. ATP binding cassette transporter G5 and G8 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin. J Lipid Res. 2004 Apr; 45(4):653-6. PMID: 14703505.
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    179. Kajinami K, Brousseau ME, Ordovas JM, Schaefer EJ. CYP3A4 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin in primary hypercholesterolemia. Am J Cardiol. 2004 Jan 1; 93(1):104-7. PMID: 14697480.
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    180. Elosua R, Demissie S, Cupples LA, Meigs JB, Wilson PW, Schaefer EJ, Corella D, Ordovas JM. Obesity modulates the association among APOE genotype, insulin, and glucose in men. Obes Res. 2003 Dec; 11(12):1502-8. PMID: 14694215.
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    181. Asztalos BF, Horvath KV, Kajinami K, Nartsupha C, Cox CE, Batista M, Schaefer EJ, Inazu A, Mabuchi H. Apolipoprotein composition of HDL in cholesteryl ester transfer protein deficiency. J Lipid Res. 2004 Mar; 45(3):448-55. PMID: 14657195.
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    182. Li Z, Otvos JD, Lamon-Fava S, Carrasco WV, Lichtenstein AH, McNamara JR, Ordovas JM, Schaefer EJ. Men and women differ in lipoprotein response to dietary saturated fat and cholesterol restriction. J Nutr. 2003 Nov; 133(11):3428-33. PMID: 14608054.
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    183. Kroes R, Schaefer EJ, Squire RA, Williams GM. A review of the safety of DHA45-oil. Food Chem Toxicol. 2003 Nov; 41(11):1433-46. PMID: 12962995.
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    184. Barzilai N, Atzmon G, Schechter C, Schaefer EJ, Cupples AL, Lipton R, Cheng S, Shuldiner AR. Unique lipoprotein phenotype and genotype associated with exceptional longevity. JAMA. 2003 Oct 15; 290(15):2030-40. PMID: 14559957.
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    185. Lamon-Fava S, Posfai B, Asztalos BF, Horvath KV, Dallal GE, Schaefer EJ. Effects of estrogen and medroxyprogesterone acetate on subpopulations of triglyceride-rich lipoproteins and high-density lipoproteins. Metabolism. 2003 Oct; 52(10):1330-6. PMID: 14564686.
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    186. Osgood D, Corella D, Demissie S, Cupples LA, Wilson PW, Meigs JB, Schaefer EJ, Coltell O, Ordovas JM. Genetic variation at the scavenger receptor class B type I gene locus determines plasma lipoprotein concentrations and particle size and interacts with type 2 diabetes: the framingham study. J Clin Endocrinol Metab. 2003 Jun; 88(6):2869-79. PMID: 12788901.
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    187. Robins SJ, Rubins HB, Faas FH, Schaefer EJ, Elam MB, Anderson JW, Collins D. Insulin resistance and cardiovascular events with low HDL cholesterol: the Veterans Affairs HDL Intervention Trial (VA-HIT). Diabetes Care. 2003 May; 26(5):1513-7. PMID: 12716814.
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    188. Asztalos BF, Schaefer EJ. High-density lipoprotein subpopulations in pathologic conditions. Am J Cardiol. 2003 Apr 3; 91(7A):12E-17E. PMID: 12679198.
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    189. Santos MS, Lichtenstein AH, Leka LS, Goldin B, Schaefer EJ, Meydani SN. Immunological effects of low-fat diets with and without weight loss. J Am Coll Nutr. 2003 Apr; 22(2):174-82. PMID: 12672714.
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    190. Kijima T, Maulik G, Ma PC, Madhiwala P, Schaefer E, Salgia R. Fibronectin enhances viability and alters cytoskeletal functions (with effects on the phosphatidylinositol 3-kinase pathway) in small cell lung cancer. J Cell Mol Med. 2003 Apr-Jun; 7(2):157-64. PMID: 12927054.
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    191. Asztalos BF, Batista M, Horvath KV, Cox CE, Dallal GE, Morse JS, Brown GB, Schaefer EJ. Change in alpha1 HDL concentration predicts progression in coronary artery stenosis. Arterioscler Thromb Vasc Biol. 2003 May 1; 23(5):847-52. PMID: 12637338.
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    192. Sprecher DL, Watkins TR, Behar S, Brown WV, Rubins HB, Schaefer EJ. Importance of high-density lipoprotein cholesterol and triglyceride levels in coronary heart disease. Am J Cardiol. 2003 Mar 1; 91(5):575-80. PMID: 12615263.
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    193. Asztalos BF, Schaefer EJ. HDL in atherosclerosis: actor or bystander? Atheroscler Suppl. 2003 Mar; 4(1):21-9. PMID: 12714034.
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    194. Matthan NR, Giovanni A, Schaefer EJ, Brown BG, Lichtenstein AH. Impact of simvastatin, niacin, and/or antioxidants on cholesterol metabolism in CAD patients with low HDL. J Lipid Res. 2003 Apr; 44(4):800-6. PMID: 12562840.
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    195. Lamon-Fava S, Posfai B, Schaefer EJ. Effect of hormonal replacement therapy on C-reactive protein and cell-adhesion molecules in postmenopausal women. Am J Cardiol. 2003 Jan 15; 91(2):252-4. PMID: 12521647.
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    196. Rubins HB, Robins SJ, Collins D, Nelson DB, Elam MB, Schaefer EJ, Faas FH, Anderson JW. Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT). Arch Intern Med. 2002 Dec 9-23; 162(22):2597-604. PMID: 12456232.
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    197. Hays NP, Bathalon GP, Meydani SN, Leka LS, Lipman R, Roubenoff R, Schaefer EJ, Roberts SB. Metabolic aging and predicted longevity: results of a cross-sectional study in post-menopausal women. Aging Clin Exp Res. 2002 Dec; 14(6):465-73. PMID: 12674486.
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    198. Bermudez OI, Velez-Carrasco W, Schaefer EJ, Tucker KL. Dietary and plasma lipid, lipoprotein, and apolipoprotein profiles among elderly Hispanics and non-Hispanics and their association with diabetes. Am J Clin Nutr. 2002 Dec; 76(6):1214-21. PMID: 12450885.
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    199. Lichtenstein AH, Jalbert SM, Adlercreutz H, Goldin BR, Rasmussen H, Schaefer EJ, Ausman LM. Lipoprotein response to diets high in soy or animal protein with and without isoflavones in moderately hypercholesterolemic subjects. Arterioscler Thromb Vasc Biol. 2002 Nov 1; 22(11):1852-8. PMID: 12426215.
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    200. Ordovas JM, Corella D, Demissie S, Cupples LA, Couture P, Coltell O, Wilson PW, Schaefer EJ, Tucker KL. Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: evidence of a strong dose effect in this gene-nutrient interaction in the Framingham Study. Circulation. 2002 Oct 29; 106(18):2315-21. PMID: 12403660.
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    202. Asztalos BF, Horvath KV, McNamara JR, Roheim PS, Rubinstein JJ, Schaefer EJ. Comparing the effects of five different statins on the HDL subpopulation profiles of coronary heart disease patients. Atherosclerosis. 2002 Oct; 164(2):361-9. PMID: 12204809.
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    203. Gleason JA, Bourdet KL, Koehn K, Holay SY, Schaefer EJ. Cardiovascular risk reduction and dietary compliance with a home-delivered diet and lifestyle modification program. J Am Diet Assoc. 2002 Oct; 102(10):1445-51. PMID: 12396164.
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    205. Schaefer EJ. Importance of dietary management and practical patient counseling--US perspective. Atheroscler Suppl. 2002 Oct; 3(3):17-22. PMID: 12429169.
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    206. Maulik G, Madhiwala P, Brooks S, Ma PC, Kijima T, Tibaldi EV, Schaefer E, Parmar K, Salgia R. Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer. J Cell Mol Med. 2002 Oct-Dec; 6(4):539-53. PMID: 12611639.
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    207. Brousseau ME, Schaefer EJ. New targets for medical treatment of lipid disorders. Curr Atheroscler Rep. 2002 Sep; 4(5):343-9. PMID: 12162933.
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    210. Schaefer EJ, McNamara JR, Shah PK, Nakajima K, Cupples LA, Ordovas JM, Wilson PW. Elevated remnant-like particle cholesterol and triglyceride levels in diabetic men and women in the Framingham Offspring Study. Diabetes Care. 2002 Jun; 25(6):989-94. PMID: 12032104.
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    212. Tai ES, Demissie S, Cupples LA, Corella D, Wilson PW, Schaefer EJ, Ordovas JM. Association between the PPARA L162V polymorphism and plasma lipid levels: the Framingham Offspring Study. Arterioscler Thromb Vasc Biol. 2002 May 1; 22(5):805-10. PMID: 12006394.
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    213. Batiste MC, Schaefer EJ. Diagnosis and management of lipoprotein abnormalities. Nutr Clin Care. 2002 May-Jun; 5(3):115-23. PMID: 12134566.
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    215. Lamon-Fava S, Schaefer EJ, Garuti R, Salen G, Calandra S. Two novel mutations in the sterol 27-hydroxylase gene causing cerebrotendinous xanthomatosis. Clin Genet. 2002 Mar; 61(3):185-91. PMID: 12000359.
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    216. Han SN, Leka LS, Lichtenstein AH, Ausman LM, Schaefer EJ, Meydani SN. Effect of hydrogenated and saturated, relative to polyunsaturated, fat on immune and inflammatory responses of adults with moderate hypercholesterolemia. J Lipid Res. 2002 Mar; 43(3):445-52. PMID: 11893781.
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    217. Lichtenstein AH, Ausman LM, Jalbert SM, Vilella-Bach M, Jauhiainen M, McGladdery S, Erkkilä AT, Ehnholm C, Frohlich J, Schaefer EJ. Efficacy of a Therapeutic Lifestyle Change/Step 2 diet in moderately hypercholesterolemic middle-aged and elderly female and male subjects. J Lipid Res. 2002 Feb; 43(2):264-73. PMID: 11861668.
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    219. Ordovas JM, Corella D, Cupples LA, Demissie S, Kelleher A, Coltell O, Wilson PW, Schaefer EJ, Tucker K. Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: the Framingham Study. Am J Clin Nutr. 2002 Jan; 75(1):38-46. PMID: 11756058.
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    224. Russo GT, Meigs JB, Cupples LA, Demissie S, Otvos JD, Wilson PW, Lahoz C, Cucinotta D, Couture P, Mallory T, Schaefer EJ, Ordovas JM. Association of the Sst-I polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: the Framingham offspring study. Atherosclerosis. 2001 Sep; 158(1):173-81. PMID: 11500189.
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    225. Pedro-Botet J, Schaefer EJ, Bakker-Arkema RG, Black DM, Stein EM, Corella D, Ordovas JM. Apolipoprotein E genotype affects plasma lipid response to atorvastatin in a gender specific manner. Atherosclerosis. 2001 Sep; 158(1):183-93. PMID: 11500190.
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    226. Sun Z, Welty FK, Dolnikowski GG, Lichtenstein AH, Schaefer EJ. Effects of a National Cholesterol Education Program Step II Diet on apolipoprotein A-IV metabolism within triacylglycerol-rich lipoproteins and plasma. Am J Clin Nutr. 2001 Sep; 74(3):308-14. PMID: 11522553.
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    227. McKenney JM, McCormick LS, Schaefer EJ, Black DM, Watkins ML. Effect of niacin and atorvastatin on lipoprotein subclasses in patients with atherogenic dyslipidemia. Am J Cardiol. 2001 Aug 1; 88(3):270-4. PMID: 11472706.
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    228. Davidson MH, Maki KC, Umporowicz DM, Ingram KA, Dicklin MR, Schaefer E, Lane RW, McNamara JR, Ribaya-Mercado JD, Perrone G, Robins SJ, Franke WC. Safety and tolerability of esterified phytosterols administered in reduced-fat spread and salad dressing to healthy adult men and women. J Am Coll Nutr. 2001 Aug; 20(4):307-19. PMID: 11506058.
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    229. Maki KC, Davidson MH, Umporowicz DM, Schaefer EJ, Dicklin MR, Ingram KA, Chen S, McNamara JR, Gebhart BW, Ribaya-Mercado JD, Perrone G, Robins SJ, Franke WC. Lipid responses to plant-sterol-enriched reduced-fat spreads incorporated into a National Cholesterol Education Program Step I diet. Am J Clin Nutr. 2001 Jul; 74(1):33-43. PMID: 11451715.
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    230. Lyu LC, Yeh CY, Lichtenstein AH, Li Z, Ordovas JM, Schaefer EJ. Association of sex, adiposity, and diet with HDL subclasses in middle-aged Chinese. Am J Clin Nutr. 2001 Jul; 74(1):64-71. PMID: 11451719.
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    231. Galluzzi JR, Cupples LA, Meigs JB, Wilson PW, Schaefer EJ, Ordovas JM. Association of the Ala54-Thr polymorphism in the intestinal fatty acid-binding protein with 2-h postchallenge insulin levels in the Framingham Offspring Study. Diabetes Care. 2001 Jul; 24(7):1161-6. PMID: 11423496.
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    232. Sun Z, Lichtenstein AH, Dolnikowski GG, Welty FK, Schaefer EJ. Human apolipoprotein A-IV metabolism within triglyceride-rich lipoproteins and plasma. Atherosclerosis. 2001 Jun; 156(2):363-72. PMID: 11395033.
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    233. Camper-Kirby D, Welch S, Walker A, Shiraishi I, Setchell KD, Schaefer E, Kajstura J, Anversa P, Sussman MA. Myocardial Akt activation and gender: increased nuclear activity in females versus males. Circ Res. 2001 May 25; 88(10):1020-7. PMID: 11375271.
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    235. Vogel R, Schaefer E. Should all patients with cardiovascular disease receive statin therapy? Am J Manag Care. 2001 May; 7(5 Suppl):S117-24. PMID: 11383372.
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    236. Saltzman E, Das SK, Lichtenstein AH, Dallal GE, Corrales A, Schaefer EJ, Greenberg AS, Roberts SB. An oat-containing hypocaloric diet reduces systolic blood pressure and improves lipid profile beyond effects of weight loss in men and women. J Nutr. 2001 May; 131(5):1465-70. PMID: 11340101.
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    239. Rosenson RS, Tangney CC, Schaefer EJ. Comparative study of HMG-CoA reductase inhibitors on fibrinogen. Atherosclerosis. 2001 Apr; 155(2):463-6. PMID: 11254918.
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    240. Lichtenstein AH, Jauhiainen M, McGladdery S, Ausman LM, Jalbert SM, Vilella-Bach M, Ehnholm C, Frohlich J, Schaefer EJ. Impact of hydrogenated fat on high density lipoprotein subfractions and metabolism. J Lipid Res. 2001 Apr; 42(4):597-604. PMID: 11290832.
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    241. Millar JS, Lichtenstein AH, Ordovas JM, Dolnikowski GG, Schaefer EJ. Human triglyceride-rich lipoprotein apo E kinetics and its relationship to LDL apo B-100 metabolism. Atherosclerosis. 2001 Apr; 155(2):477-85. PMID: 11254920.
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    242. Bathalon GP, Hays NP, Meydani SN, Dawson-Hughes B, Schaefer EJ, Lipman R, Nelson M, Greenberg AS, Roberts SB. Metabolic, psychological, and health correlates of dietary restraint in healthy postmenopausal women. J Gerontol A Biol Sci Med Sci. 2001 Apr; 56(4):M206-11. PMID: 11283192.
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    243. Robins SJ, Collins D, Wittes JT, Papademetriou V, Deedwania PC, Schaefer EJ, McNamara JR, Kashyap ML, Hershman JM, Wexler LF, Rubins HB. Relation of gemfibrozil treatment and lipid levels with major coronary events: VA-HIT: a randomized controlled trial. JAMA. 2001 Mar 28; 285(12):1585-91. PMID: 11268266.
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    244. Brousseau ME, Bodzioch M, Schaefer EJ, Goldkamp AL, Kielar D, Probst M, Ordovas JM, Aslanidis C, Lackner KJ, Bloomfield Rubins H, Collins D, Robins SJ, Wilson PW, Schmitz G. Common variants in the gene encoding ATP-binding cassette transporter 1 in men with low HDL cholesterol levels and coronary heart disease. Atherosclerosis. 2001 Feb 15; 154(3):607-11. PMID: 11257261.
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    252. Jenner JL, Jacques PF, Seman LJ, Schaefer EJ. Ascorbic acid supplementation does not lower plasma lipoprotein(a) concentrations. Atherosclerosis. 2000 Aug; 151(2):541-4. PMID: 10924732.
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    253. Brousseau ME, Eberhart GP, Dupuis J, Asztalos BF, Goldkamp AL, Schaefer EJ, Freeman MW. Cellular cholesterol efflux in heterozygotes for tangier disease is markedly reduced and correlates with high density lipoprotein cholesterol concentration and particle size. J Lipid Res. 2000 Jul; 41(7):1125-35. PMID: 10884295.
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    254. Welty FK, Lichtenstein AH, Barrett PH, Jenner JL, Dolnikowski GG, Schaefer EJ. Effects of ApoE genotype on ApoB-48 and ApoB-100 kinetics with stable isotopes in humans. Arterioscler Thromb Vasc Biol. 2000 Jul; 20(7):1807-10. PMID: 10894821.
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    255. Marsh JB, Welty FK, Schaefer EJ. Stable isotope turnover of apolipoproteins of high-density lipoproteins in humans. Curr Opin Lipidol. 2000 Jun; 11(3):261-6. PMID: 10882341.
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    256. Wityk RJ, Kittner SJ, Jenner JL, Hebel JR, Epstein A, Wozniak MA, Stolley PD, Stern BJ, Sloan MA, Price TR, McCarter RJ, Macko RF, Johnson CJ, Earley CJ, Buchholz DW, Schaefer EJ. Lipoprotein (a) and the risk of ischemic stroke in young women. Atherosclerosis. 2000 Jun; 150(2):389-96. PMID: 10856531.
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    257. Shearman AM, Ordovas JM, Cupples LA, Schaefer EJ, Harmon MD, Shao Y, Keen JD, DeStefano AL, Joost O, Wilson PW, Housman DE, Myers RH. Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: a genome-wide scan in the Framingham study. Hum Mol Genet. 2000 May 22; 9(9):1315-20. PMID: 10814713.
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    258. Ordovas JM, Cupples LA, Corella D, Otvos JD, Osgood D, Martinez A, Lahoz C, Coltell O, Wilson PW, Schaefer EJ. Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: the Framingham study. Arterioscler Thromb Vasc Biol. 2000 May; 20(5):1323-9. PMID: 10807749.
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    259. Meigs JB, Ordovas JM, Cupples LA, Singer DE, Nathan DM, Schaefer EJ, Wilson PW. Apolipoprotein E isoform polymorphisms are not associated with insulin resistance: the Framingham Offspring Study. Diabetes Care. 2000 May; 23(5):669-74. PMID: 10834428.
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    260. Booth SL, Tucker KL, Chen H, Hannan MT, Gagnon DR, Cupples LA, Wilson PW, Ordovas J, Schaefer EJ, Dawson-Hughes B, Kiel DP. Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Am J Clin Nutr. 2000 May; 71(5):1201-8. PMID: 10799384.
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    262. Sussman MA, Welch S, Walker A, Klevitsky R, Hewett TE, Price RL, Schaefer E, Yager K. Altered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1. J Clin Invest. 2000 Apr; 105(7):875-86. PMID: 10749567; PMCID: PMC377478.
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    264. Schwab US, Ausman LM, Vogel S, Li Z, Lammi-Keefe CJ, Goldin BR, Ordovas JM, Schaefer EJ, Lichtenstein AH. Dietary cholesterol increases the susceptibility of low density lipoprotein to oxidative modification. Atherosclerosis. 2000 Mar; 149(1):83-90. PMID: 10704618.
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    265. Couture P, Otvos JD, Cupples LA, Lahoz C, Wilson PW, Schaefer EJ, Ordovas JM. Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles: The Framingham Offspring Study. Arterioscler Thromb Vasc Biol. 2000 Mar; 20(3):815-22. PMID: 10712408.
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    266. Brousseau ME, Schaefer EJ, Dupuis J, Eustace B, Van Eerdewegh P, Goldkamp AL, Thurston LM, FitzGerald MG, Yasek-McKenna D, O'Neill G, Eberhart GP, Weiffenbach B, Ordovas JM, Freeman MW, Brown RH, Gu JZ. Novel mutations in the gene encoding ATP-binding cassette 1 in four tangier disease kindreds. J Lipid Res. 2000 Mar; 41(3):433-41. PMID: 10706591.
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    267. Velez-Carrasco W, Lichtenstein AH, Li Z, Dolnikowski GG, Lamon-Fava S, Welty FK, Schaefer EJ. Apolipoprotein A-I and A-II kinetic parameters as assessed by endogenous labeling with [(2)H(3)]leucine in middle-aged and elderly men and women. Arterioscler Thromb Vasc Biol. 2000 Mar; 20(3):801-6. PMID: 10712406.
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    268. Schaefer EJ, Augustin JL, Schaefer MM, Rasmussen H, Ordovas JM, Dallal GE, Dwyer JT. Lack of efficacy of a food-frequency questionnaire in assessing dietary macronutrient intakes in subjects consuming diets of known composition. Am J Clin Nutr. 2000 Mar; 71(3):746-51. PMID: 10702168.
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    270. Couture P, Otvos JD, Cupples LA, Wilson PW, Schaefer EJ, Ordovas JM. Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study. Atherosclerosis. 2000 Feb; 148(2):337-43. PMID: 10657570.
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    271. Zanarini MC, Skodol AE, Bender D, Dolan R, Sanislow C, Schaefer E, Morey LC, Grilo CM, Shea MT, McGlashan TH, Gunderson JG. The Collaborative Longitudinal Personality Disorders Study: reliability of axis I and II diagnoses. J Pers Disord. 2000; 14(4):291-9. PMID: 11213787.
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    273. Lamon-Fava S, Ordovas JM, Schaefer EJ. Estrogen increases apolipoprotein (apo) A-I secretion in hep G2 cells by modulating transcription of the apo A-I gene promoter. Arterioscler Thromb Vasc Biol. 1999 Dec; 19(12):2960-5. PMID: 10591676.
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    274. Kastelein JJ, Ordovas JM, Wittekoek ME, Pimstone SN, Wilson WF, Gagné SE, Larson MG, Schaefer EJ, Boer JM, Gerdes C, Hayden MR. Two common mutations (D9N, N291S) in lipoprotein lipase: a cumulative analysis of their influence on plasma lipids and lipoproteins in men and women. Clin Genet. 1999 Oct; 56(4):297-305. PMID: 10636448.
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    275. Couture P, Otvos JD, Cupples LA, Wilson PW, Schaefer EJ, Ordovas JM. Association of the A-204C polymorphism in the cholesterol 7alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study. J Lipid Res. 1999 Oct; 40(10):1883-9. PMID: 10508208.
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    276. McNamara JR, Seman LJ, Schaefer EJ. The laboratory's role in identifying lipid and lipoprotein risk factors for CHD. MLO Med Lab Obs. 1999 Oct; 31(10):24-8, 30-6, 51; quiz 38-9. PMID: 11184276.
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    277. Mascioli EA, McLennan CE, Schaefer EJ, Lichtenstein AH, Høy CE, Christensen MS, Bistrian BR. Lipidemic effects of an interesterified mixture of butter, medium-chain triacylglycerol and safflower oils. Lipids. 1999 Sep; 34(9):889-94. PMID: 10574652.
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    279. Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, Faas FH, Linares E, Schaefer EJ, Schectman G, Wilt TJ, Wittes J. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med. 1999 Aug 5; 341(6):410-8. PMID: 10438259.
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    280. Melander A, Olsson J, Lindberg G, Salzman A, Howard T, Stang P, Lydick E, Emslie-Smith A, Boyle DI, Evans JM, Macdonald TM, Bain J, Sullivan F. 35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. Diabetologia. 1999 Aug; 42(Suppl 1):A1-A330. PMID: 27770183.
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    281. Handelman GJ, Nightingale ZD, Lichtenstein AH, Schaefer EJ, Blumberg JB. Lutein and zeaxanthin concentrations in plasma after dietary supplementation with egg yolk. Am J Clin Nutr. 1999 Aug; 70(2):247-51. PMID: 10426702.
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    282. Deckelbaum RJ, Fisher EA, Winston M, Kumanyika S, Lauer RM, Pi-Sunyer FX, St Jeor S, Schaefer EJ, Weinstein IB. Summary of a scientific conference on preventive nutrition: pediatrics to geriatrics. Circulation. 1999 Jul 27; 100(4):450-6. PMID: 10421609.
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    284. Ordovas JM, Schaefer EJ. Treatment of dyslipidemia: genetic interactions with diet and drug therapy. Curr Atheroscler Rep. 1999 Jul; 1(1):16-23. PMID: 11122687.
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    286. Lichtenstein AH, Ausman LM, Jalbert SM, Schaefer EJ. Effects of different forms of dietary hydrogenated fats on serum lipoprotein cholesterol levels. N Engl J Med. 1999 Jun 24; 340(25):1933-40. PMID: 10379016.
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    287. Gagné SE, Larson MG, Pimstone SN, Schaefer EJ, Kastelein JJ, Wilson PW, Ordovas JM, Hayden MR. A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study. Clin Genet. 1999 Jun; 55(6):450-4. PMID: 10450862.
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    288. Vélez-Carrasco W, Lichtenstein AH, Welty FK, Li Z, Lamon-Fava S, Dolnikowski GG, Schaefer EJ. Dietary restriction of saturated fat and cholesterol decreases HDL ApoA-I secretion. Arterioscler Thromb Vasc Biol. 1999 Apr; 19(4):918-24. PMID: 10195918.
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    289. Seman LJ, McNamara JR, Schaefer EJ. Lipoprotein(a), homocysteine, and remnantlike particles: emerging risk factors. Curr Opin Cardiol. 1999 Mar; 14(2):186-91. PMID: 10191979.
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    290. Tucker KL, Chen H, Vogel S, Wilson PW, Schaefer EJ, Lammi-Keefe CJ. Carotenoid intakes, assessed by dietary questionnaire, are associated with plasma carotenoid concentrations in an elderly population. J Nutr. 1999 Feb; 129(2):438-45. PMID: 10024624.
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    291. Ehrenberg BL, Lamon-Fava S, Corbett KE, McNamara JR, Dallal GE, Schaefer EJ. Comparison of the effects of pravastatin and lovastatin on sleep disturbance in hypercholesterolemic subjects. Sleep. 1999 Feb 1; 22(1):117-21. PMID: 9989373.
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    292. Eisen SV, Wilcox M, Leff HS, Schaefer E, Culhane MA. Assessing behavioral health outcomes in outpatient programs: reliability and validity of the BASIS-32. J Behav Health Serv Res. 1999 Feb; 26(1):5-17. PMID: 10069137.
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    296. Schwab US, Vogel S, Lammi-Keefe CJ, Ordovas JM, Schaefer EJ, Li Z, Ausman LM, Gualtieri L, Goldin BR, Furr HC, Lichtenstein AH. Varying dietary fat type of reduced-fat diets has little effect on the susceptibility of LDL to oxidative modification in moderately hypercholesterolemic subjects. J Nutr. 1998 Oct; 128(10):1703-9. PMID: 9772139.
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    297. Judd JT, Baer DJ, Clevidence BA, Muesing RA, Chen SC, Weststrate JA, Meijer GW, Wittes J, Lichtenstein AH, Vilella-Bach M, Schaefer EJ. Effects of margarine compared with those of butter on blood lipid profiles related to cardiovascular disease risk factors in normolipemic adults fed controlled diets. Am J Clin Nutr. 1998 Oct; 68(4):768-77. PMID: 9771853.
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    302. Schwab US, Sarkkinen ES, Lichtenstein AH, Li Z, Ordovas JM, Schaefer EJ, Uusitupa MI. The effect of quality and amount of dietary fat on the susceptibility of low density lipoprotein to oxidation in subjects with impaired glucose tolerance. Eur J Clin Nutr. 1998 Jun; 52(6):452-8. PMID: 9683400.
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    303. Lamon-Fava S, Sadowski JA, Davidson KW, O'Brien ME, McNamara JR, Schaefer EJ. Plasma lipoproteins as carriers of phylloquinone (vitamin K1) in humans. Am J Clin Nutr. 1998 Jun; 67(6):1226-31. PMID: 9625097.
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    304. O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ, Myers RH, Levy D. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study. Circulation. 1998 May 12; 97(18):1766-72. PMID: 9603529.
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    306. Karge WH, Schaefer EJ, Ordovas JM. Quantification of mRNA by polymerase chain reaction (PCR) using an internal standard and a nonradioactive detection method. Methods Mol Biol. 1998; 110:43-61. PMID: 9918038.
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    308. Ehrenborg E, Clee SM, Pimstone SN, Reymer PW, Benlian P, Hoogendijk CF, Davis HJ, Bissada N, Miao L, Gagné SE, Greenberg LJ, Henry R, Henderson H, Ordovas JM, Schaefer EJ, Kastelein JJ, Kotze MJ, Hayden MR. Ethnic variation and in vivo effects of the -93t-->g promoter variant in the lipoprotein lipase gene. Arterioscler Thromb Vasc Biol. 1997 Nov; 17(11):2672-8. PMID: 9409241.
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    315. Campos H, López-Miranda J, Rodríguez C, Albajar M, Schaefer EJ, Ordovás JM. Urbanization elicits a more atherogenic lipoprotein profile in carriers of the apolipoprotein A-IV-2 allele than in A-IV-1 homozygotes. Arterioscler Thromb Vasc Biol. 1997 Jun; 17(6):1074-81. PMID: 9194757.
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    320. Nelson GJ, Schmidt PC, Bartolini G, Kelley DS, Phinney SD, Kyle D, Silbermann S, Schaefer EJ. The effect of dietary arachidonic acid on plasma lipoprotein distributions, apoproteins, blood lipid levels, and tissue fatty acid composition in humans. Lipids. 1997 Apr; 32(4):427-33. PMID: 9113632.
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    326. Wilson PW, Schaefer EJ, Larson MG, Ordovas JM. Apolipoprotein E alleles and risk of coronary disease. A meta-analysis. Arterioscler Thromb Vasc Biol. 1996 Oct; 16(10):1250-5. PMID: 8857921.
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    327. Siegel RD, Cupples A, Schaefer EJ, Wilson PW. Lipoproteins, apolipoproteins, and low-density lipoprotein size among diabetics in the Framingham offspring study. Metabolism. 1996 Oct; 45(10):1267-72. PMID: 8843183.
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    330. Craig SB, Bandini LG, Lichtenstein AH, Schaefer EJ, Dietz WH. The impact of physical activity on lipids, lipoproteins, and blood pressure in preadolescent girls. Pediatrics. 1996 Sep; 98(3 Pt 1):389-95. PMID: 8784362.
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    421. Civeira F, Genest J, Pocovi M, Salem DN, Herbert PN, Wilson PW, Schaefer EJ, Ordovas JM. The MspI restriction fragment length polymorphism 3' to the apolipoprotein A-II gene: relationships with lipids, apolipoproteins, and premature coronary artery disease. Atherosclerosis. 1992 Feb; 92(2-3):165-76. PMID: 1352975.
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    422. Stucchi AF, Hennessy LK, Vespa DB, Weiner EJ, Osada J, Ordovas JM, Schaefer EJ, Nicolosi RJ. Effect of corn and coconut oil-containing diets with and without cholesterol on high density lipoprotein apoprotein A-I metabolism and hepatic apoprotein A-I mRNA levels in cebus monkeys. Arterioscler Thromb. 1991 Nov-Dec; 11(6):1719-29. PMID: 1931873.
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    423. Lamon-Fava S, Jimenez D, Christian JC, Fabsitz RR, Reed T, Carmelli D, Castelli WP, Ordovas JM, Wilson PW, Schaefer EJ. The NHLBI Twin Study: heritability of apolipoprotein A-I, B, and low density lipoprotein subclasses and concordance for lipoprotein(a). Atherosclerosis. 1991 Nov; 91(1-2):97-106. PMID: 1839820.
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    424. Genest JJ, Bard JM, Fruchart JC, Ordovas JM, Wilson PF, Schaefer EJ. Plasma apolipoprotein A-I, A-II, B, E and C-III containing particles in men with premature coronary artery disease. Atherosclerosis. 1991 Oct; 90(2-3):149-57. PMID: 1684707.
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    425. Meydani SN, Lichtenstein AH, White PJ, Goodnight SH, Elson CE, Woods M, Gorbach SL, Schaefer EJ. Food use and health effects of soybean and sunflower oils. J Am Coll Nutr. 1991 Oct; 10(5):406-28. PMID: 1955619.
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    426. Schaefer EJ. High density lipoproteins and coronary artery disease. Can J Cardiol. 1991 Oct; 7(8):VIII-IX. PMID: 1742666.
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    427. Genest JJ, McNamara JR, Upson B, Salem DN, Ordovas JM, Schaefer EJ, Malinow MR. Prevalence of familial hyperhomocyst(e)inemia in men with premature coronary artery disease. Arterioscler Thromb. 1991 Sep-Oct; 11(5):1129-36. PMID: 1911700.
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    428. Farber HW, Schaefer EJ, Franey R, Grimaldi R, Hill NS. The endurance triathlon: metabolic changes after each event and during recovery. Med Sci Sports Exerc. 1991 Aug; 23(8):959-65. PMID: 1956272.
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    429. Campos H, Bailey SM, Gussak LS, Siles X, Ordovas JM, Schaefer EJ. Relations of body habitus, fitness level, and cardiovascular risk factors including lipoproteins and apolipoproteins in a rural and urban Costa Rican population. Arterioscler Thromb. 1991 Jul-Aug; 11(4):1077-88. PMID: 2065029.
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    430. Campos H, Willett WC, Peterson RM, Siles X, Bailey SM, Wilson PW, Posner BM, Ordovas JM, Schaefer EJ. Nutrient intake comparisons between Framingham and rural and Urban Puriscal, Costa Rica. Associations with lipoproteins, apolipoproteins, and low density lipoprotein particle size. Arterioscler Thromb. 1991 Jul-Aug; 11(4):1089-99. PMID: 2065030.
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    431. Genest JJ, McNamara JR, Salem DN, Schaefer EJ. Prevalence of risk factors in men with premature coronary artery disease. Am J Cardiol. 1991 Jun 1; 67(15):1185-9. PMID: 2035438.
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    432. Genest J, Jenner JL, McNamara JR, Ordovas JM, Silberman SR, Wilson PW, Schaefer EJ. Prevalence of lipoprotein (a) [Lp(a)] excess in coronary artery disease. Am J Cardiol. 1991 May 15; 67(13):1039-145. PMID: 1827234.
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    433. Meydani M, Natiello F, Goldin B, Free N, Woods M, Schaefer E, Blumberg JB, Gorbach SL. Effect of long-term fish oil supplementation on vitamin E status and lipid peroxidation in women. J Nutr. 1991 Apr; 121(4):484-91. PMID: 1826131.
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    434. Wardell MR, Rall SC, Schaefer EJ, Kane JP, Weisgraber KH. Two apolipoprotein E5 variants illustrate the importance of the position of additional positive charge on receptor-binding activity. J Lipid Res. 1991 Mar; 32(3):521-8. PMID: 1648586.
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    435. Reed T, Christian JC, Wood PD, Schaefer EJ. Influence of placentation on high density lipoproteins in adult males: the NHLBI twin study. Acta Genet Med Gemellol (Roma). 1991; 40(3-4):353-9. PMID: 1821512.
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    436. Genest JJ, McNamara JR, Salem DN, Wilson PW, Schaefer EJ, Malinow MR. Plasma homocyst(e)ine levels in men with premature coronary artery disease. J Am Coll Cardiol. 1990 Nov; 16(5):1114-9. PMID: 2229757.
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    437. Hunninghake DB, Knopp RH, Schonfeld G, Goldberg AC, Brown WV, Schaefer EJ, Margolis S, Dobs AS, Mellies MJ, Insull W, et al. Efficacy and safety of pravastatin in patients with primary hypercholesterolemia. I. A dose-response study. Atherosclerosis. 1990 Nov; 85(1):81-9. PMID: 2126437.
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    438. Dupont J, White PJ, Carpenter MP, Schaefer EJ, Meydani SN, Elson CE, Woods M, Gorbach SL. Food uses and health effects of corn oil. J Am Coll Nutr. 1990 Oct; 9(5):438-70. PMID: 2258533.
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    439. Campos H, Wilson PW, Jiménez D, McNamara JR, Ordovas J, Schaefer EJ. Differences in apolipoproteins and low-density lipoprotein subfractions in postmenopausal women on and off estrogen therapy: results from the Framingham Offspring Study. Metabolism. 1990 Oct; 39(10):1033-8. PMID: 2120547.
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    440. Lichtenstein AH, Cohn JS, Hachey DL, Millar JS, Ordovas JM, Schaefer EJ. Comparison of deuterated leucine, valine, and lysine in the measurement of human apolipoprotein A-I and B-100 kinetics. J Lipid Res. 1990 Sep; 31(9):1693-701. PMID: 2123232.
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    441. Chee KM, Gong JX, Rees DM, Meydani M, Ausman L, Johnson J, Siguel EN, Schaefer EJ. Fatty acid content of marine oil capsules. Lipids. 1990 Sep; 25(9):523-8. PMID: 2250588.
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    442. Krasinski SD, Cohn JS, Russell RM, Schaefer EJ. Postprandial plasma vitamin A metabolism in humans: a reassessment of the use of plasma retinyl esters as markers for intestinally derived chylomicrons and their remnants. Metabolism. 1990 Apr; 39(4):357-65. PMID: 2325560.
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    443. Kaufman HW, McNamara JR, Anderson KM, Wilson PW, Schaefer EJ. How reliably can compact chemistry analyzers measure lipids? JAMA. 1990 Mar 2; 263(9):1245-9. PMID: 2304240.
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    444. Cohn JS, Wagner DA, Cohn SD, Millar JS, Schaefer EJ. Measurement of very low density and low density lipoprotein apolipoprotein (Apo) B-100 and high density lipoprotein Apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding. J Clin Invest. 1990 Mar; 85(3):804-11. PMID: 2107210; PMCID: PMC296498.
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    445. Krasinski SD, Cohn JS, Schaefer EJ, Russell RM. Postprandial plasma retinyl ester response is greater in older subjects compared with younger subjects. Evidence for delayed plasma clearance of intestinal lipoproteins. J Clin Invest. 1990 Mar; 85(3):883-92. PMID: 2312731; PMCID: PMC296506.
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    446. Genest JJ, McNamara JR, Ordovas JM, Martin-Munley S, Jenner JL, Millar J, Salem DN, Schaefer EJ. Effect of elective hospitalization on plasma lipoprotein cholesterol and apolipoproteins A-I, B and Lp(a). Am J Cardiol. 1990 Mar 1; 65(9):677-9. PMID: 2106773.
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    447. Choi ES, McGandy RB, Dallal GE, Russell RM, Jacob RA, Schaefer EJ, Sadowski JA. The prevalence of cardiovascular risk factors among elderly Chinese Americans. Arch Intern Med. 1990 Feb; 150(2):413-8. PMID: 2302017.
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    448. McNamara JR, Cohn JS, Wilson PW, Schaefer EJ. Calculated values for low-density lipoprotein cholesterol in the assessment of lipid abnormalities and coronary disease risk. Clin Chem. 1990 Jan; 36(1):36-42. PMID: 2297935.
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    449. Nicolosi RJ, Stucchi AF, Kowala MC, Hennessy LK, Hegsted DM, Schaefer EJ. Effect of dietary fat saturation and cholesterol on LDL composition and metabolism. In vivo studies of receptor and nonreceptor-mediated catabolism of LDL in cebus monkeys. Arteriosclerosis. 1990 Jan-Feb; 10(1):119-28. PMID: 2297342.
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    450. Gorbach SL, Schaefer EJ, Woods M, Longcope C, Dwyer JT, Goldin BR, Morrill-LaBrode A, Dallal G. Plasma lipoprotein cholesterol and endogenous sex hormones in healthy young women. Metabolism. 1989 Nov; 38(11):1077-81. PMID: 2811678.
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    451. Ordovas JM, Cassidy DK, Civeira F, Bisgaier CL, Schaefer EJ. Familial apolipoprotein A-I, C-III, and A-IV deficiency and premature atherosclerosis due to deletion of a gene complex on chromosome 11. J Biol Chem. 1989 Oct 5; 264(28):16339-42. PMID: 2506176.
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    452. Lamon-Fava S, McNamara JR, Farber HW, Hill NS, Schaefer EJ. Acute changes in lipid, lipoprotein, apolipoprotein, and low-density lipoprotein particle size after an endurance triathlon. Metabolism. 1989 Sep; 38(9):921-5. PMID: 2505019.
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    453. Meydani M, Cohn JS, Macauley JB, McNamara JR, Blumberg JB, Schaefer EJ. Postprandial changes in the plasma concentration of alpha- and gamma-tocopherol in human subjects fed a fat-rich meal supplemented with fat-soluble vitamins. J Nutr. 1989 Sep; 119(9):1252-8. PMID: 2795239.
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    454. Breslow JL, Deeb S, Lalouel JM, Le Boeuf R, Schaefer EJ, Tyroler HA, Wilson P, Young S. Genetic susceptibility to atherosclerosis. Circulation. 1989 Sep; 80(3):724-8. PMID: 2670322.
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    455. Civeira F, Cassidy DK, Schaefer EJ, Ordovas JM. Three different insertion polymorphisms 3' to the human apolipoprotein A-IV gene. Nucleic Acids Res. 1989 Aug 11; 17(15):6428. PMID: 2570407; PMCID: PMC318327.
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    456. Cohn JS, McNamara JR, Krasinski SD, Russell RM, Schaefer EJ. Role of triglyceride-rich lipoproteins from the liver and intestine in the etiology of postprandial peaks in plasma triglyceride concentration. Metabolism. 1989 May; 38(5):484-90. PMID: 2725288.
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    457. McNamara JR, Campos H, Adolphson JL, Ordovas JM, Wilson PW, Albers JJ, Usher DC, Schaefer EJ. Screening for lipoprotein[a] elevations in plasma and assessment of size heterogeneity using gradient gel electrophoresis. J Lipid Res. 1989 May; 30(5):747-55. PMID: 2527287.
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    458. Schaefer EJ, Moussa PB, Wilson PW, McGee D, Dallal G, Castelli WP. Plasma lipoproteins in healthy octogenarians: lack of reduced high density lipoprotein cholesterol levels: results from the Framingham Heart Study. Metabolism. 1989 Apr; 38(4):293-6. PMID: 2725273.
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    459. Dallal GE, Choi E, Jacques P, Schaefer EJ, Jacob RA. Ascorbic acid, HDL cholesterol, and apolipoprotein A-I in an elderly Chinese population in Boston. J Am Coll Nutr. 1989 Feb; 8(1):69-74. PMID: 2494247.
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    460. Lamon-Fava S, Fisher EC, Nelson ME, Evans WJ, Millar JS, Ordovas JM, Schaefer EJ. Effect of exercise and menstrual cycle status on plasma lipids, low density lipoprotein particle size, and apolipoproteins. J Clin Endocrinol Metab. 1989 Jan; 68(1):17-21. PMID: 2491859.
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    461. Cohn JS, McNamara JR, Schaefer EJ. Lipoprotein cholesterol concentrations in the plasma of human subjects as measured in the fed and fasted states. Clin Chem. 1988 Dec; 34(12):2456-9. PMID: 3197284.
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    462. Samuel P, Kirkendall W, Schaefer EJ, Chin B, Schoenfeld BH, Gonasun LM, Lieberman S. Effects of isradipine, a new calcium antagonist, versus hydrochlorothiazide on serum lipids and apolipoproteins in patients with systemic hypertension. Am J Cardiol. 1988 Nov 15; 62(16):1068-71. PMID: 2973219.
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    463. Triau JE, Meydani SN, Schaefer EJ. Oxidized low density lipoprotein stimulates prostacyclin production by adult human vascular endothelial cells. Arteriosclerosis. 1988 Nov-Dec; 8(6):810-8. PMID: 3143346.
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    464. Genest JJ, Ordovas JM, Robbins AH, King DC, Frossard PM, Schaefer EJ. Two new ApoB gene polymorphisms: Rs3 and Rs4. Nucleic Acids Res. 1988 Sep 12; 16(17):8747. PMID: 2901734; PMCID: PMC338625.
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    465. Genest JJ, Ordovas MJ, Robbins AH, King DC, Frossard PM, Schaefer EJ. Two new ApoB gene polymorphisms: Rs1 and Rs2. Nucleic Acids Res. 1988 Sep 12; 16(17):8746. PMID: 2901733; PMCID: PMC338624.
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    466. Campos H, McNamara JR, Wilson PW, Ordovas JM, Schaefer EJ. Differences in low density lipoprotein subfractions and apolipoproteins in premenopausal and postmenopausal women. J Clin Endocrinol Metab. 1988 Jul; 67(1):30-5. PMID: 3379134.
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    467. Cohn JS, McNamara JR, Cohn SD, Ordovas JM, Schaefer EJ. Plasma apolipoprotein changes in the triglyceride-rich lipoprotein fraction of human subjects fed a fat-rich meal. J Lipid Res. 1988 Jul; 29(7):925-36. PMID: 3411251.
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    468. Kuecherer HF, Ruffmann K, Schaefer E, Kuebler W. Doppler echocardiographic assessment of left ventricular filling dynamics in patients with coronary heart disease and normal systolic function. Eur Heart J. 1988 Jun; 9(6):649-56. PMID: 3409895.
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    469. Rosenberg IH, Schaefer EJ. Dietary saturated fatty acids and blood cholesterol. N Engl J Med. 1988 May 12; 318(19):1270-1. PMID: 3362180.
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    470. Genest JJ, Corbett HM, McNamara JR, Schaefer MM, Salem DN, Schaefer EJ. Effect of hospitalization on high-density lipoprotein cholesterol in patients undergoing elective coronary angiography. Am J Cardiol. 1988 May 1; 61(13):998-1000. PMID: 2896455.
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    471. Schaefer EJ, McNamara JR, Genest J, Ordovas JM. Clinical significance of hypertriglyceridemia. Semin Thromb Hemost. 1988 Apr; 14(2):143-8. PMID: 3061000.
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    472. Cohn JS, McNamara JR, Cohn SD, Ordovas JM, Schaefer EJ. Postprandial plasma lipoprotein changes in human subjects of different ages. J Lipid Res. 1988 Apr; 29(4):469-79. PMID: 3392464.
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    473. Hughes TE, Ordovas JM, Schaefer EJ. Regulation of intestinal apolipoprotein B synthesis and secretion by Caco-2 cells. Lack of fatty acid effects and control by intracellular calcium ion. J Biol Chem. 1988 Mar 5; 263(7):3425-31. PMID: 3125180.
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    474. Kücherer H, Ruffmann K, Schaefer E, Kübler W. [Noninvasive determination of left ventricular diastolic filling parameters using Doppler echocardiography: clinical application in patients with coronary heart disease]. Z Kardiol. 1988 Mar; 77(3):179-84. PMID: 3381555.
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    475. Schaefer EJ. When and how to treat the dyslipidemias. Hosp Pract (Off Ed). 1988 Jan 15; 23(1):69-80, 83-4. PMID: 3121656.
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    476. Ordovas JM, King DC, Schaefer EJ. Genetic HDL deficiency states. Adv Exp Med Biol. 1988; 243:61-5. PMID: 3146916.
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    477. Ordovas JM, Schaefer EJ. Coronary artery disease, lipid disorders and genetic polymorphisms. Ann Biol Clin (Paris). 1988; 46(1):24-9. PMID: 2898907.
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    478. Schaefer EJ, McNamara JR, Genest J, Ordovas JM. Genetics and abnormalities in metabolism of lipoproteins. Clin Chem. 1988; 34(8B):B9-12. PMID: 3042205.
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    479. Prioli RP, Ordovas JM, Rosenberg I, Schaefer EJ, Pereira ME. Similarity of cruzin, an inhibitor of Trypanosoma cruzi neuraminidase, to high-density lipoprotein. Science. 1987 Dec 4; 238(4832):1417-9. PMID: 3120314.
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    480. Siguel EN, Chee KM, Gong JX, Schaefer EJ. Criteria for essential fatty acid deficiency in plasma as assessed by capillary column gas-liquid chromatography. Clin Chem. 1987 Oct; 33(10):1869-73. PMID: 3665042.
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    481. Ordovas JM, Peterson JP, Santaniello P, Cohn JS, Wilson PW, Schaefer EJ. Enzyme-linked immunosorbent assay for human plasma apolipoprotein B. J Lipid Res. 1987 Oct; 28(10):1216-24. PMID: 3681146.
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    482. McNamara JR, Campos H, Ordovas JM, Peterson J, Wilson PW, Schaefer EJ. Effect of gender, age, and lipid status on low density lipoprotein subfraction distribution. Results from the Framingham Offspring Study. Arteriosclerosis. 1987 Sep-Oct; 7(5):483-90. PMID: 3675308.
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    483. Woods M, Schaefer EJ, Morrill A, Goldin BR, Longcope C, Dwyer JD, Gorbach SL. Effect of menstrual cycle phase on plasma lipids. J Clin Endocrinol Metab. 1987 Aug; 65(2):321-3. PMID: 3597711.
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    484. Lamon-Fava S, Ordovas JM, Mandel G, Forte TM, Goodman RH, Schaefer EJ. Secretion of apolipoprotein A-I in lipoprotein particles following transfection of the human apolipoprotein A-I gene into 3T3 cells. J Biol Chem. 1987 Jul 5; 262(19):8944-7. PMID: 3110151.
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    485. McNamara JR, Schaefer EJ. Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions. Clin Chim Acta. 1987 Jun 30; 166(1):1-8. PMID: 3608193.
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    486. Ordovas JM, Litwack-Klein L, Wilson PW, Schaefer MM, Schaefer EJ. Apolipoprotein E isoform phenotyping methodology and population frequency with identification of apoE1 and apoE5 isoforms. J Lipid Res. 1987 Apr; 28(4):371-80. PMID: 3585172.
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    487. Hughes TE, Sasak WV, Ordovas JM, Forte TM, Lamon-Fava S, Schaefer EJ. A novel cell line (Caco-2) for the study of intestinal lipoprotein synthesis. J Biol Chem. 1987 Mar 15; 262(8):3762-7. PMID: 3818664.
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    488. Cohn JS, Schaefer EJ. Sample lipolysis for quantification of apolipoprotein B. Clin Chem. 1987 Feb; 33(2 Pt 1):338-9. PMID: 3802522.
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    489. Samuel P, Chin B, Schoenfeld BH, Schaefer EJ, Gonasun LM. Comparison of the effect of pindolol vs propranolol on the lipid profile in patients treated for hypertension. Br J Clin Pharmacol. 1987; 24 Suppl 1:63S-64S. PMID: 3326636; PMCID: PMC1386213.
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    490. Schaefer EJ, Gregg RE, Ghiselli G, Forte TM, Ordovas JM, Zech LA, Brewer HB. Familial apolipoprotein E deficiency. J Clin Invest. 1986 Nov; 78(5):1206-19. PMID: 3771793; PMCID: PMC423806.
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    491. Gregg RE, Zech LA, Schaefer EJ, Stark D, Wilson D, Brewer HB. Abnormal in vivo metabolism of apolipoprotein E4 in humans. J Clin Invest. 1986 Sep; 78(3):815-21. PMID: 3745440; PMCID: PMC423680.
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    492. Ordovas JM, Schaefer EJ, Salem D, Ward RH, Glueck CJ, Vergani C, Wilson PW, Karathanasis SK. Apolipoprotein A-I gene polymorphism associated with premature coronary artery disease and familial hypoalphalipoproteinemia. N Engl J Med. 1986 Mar 13; 314(11):671-7. PMID: 3081805.
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    493. Schaefer EJ, Ordovas JM. Metabolism of apolipoproteins A-I, A-II, and A-IV. Methods Enzymol. 1986; 129:420-43. PMID: 3088395.
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    494. Schaefer EJ, McNamara JR, Mitri CJ, Ordovas JM. Genetic high density lipoprotein deficiency states and atherosclerosis. Adv Exp Med Biol. 1986; 201:1-15. PMID: 3099550.
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    495. Jahn CE, Schaefer EJ, Taam LA, Hoofnagle JH, Lindgren FT, Albers JJ, Jones EA, Brewer HB. Lipoprotein abnormalities in primary biliary cirrhosis. Association with hepatic lipase inhibition as well as altered cholesterol esterification. Gastroenterology. 1985 Dec; 89(6):1266-78. PMID: 4054519.
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    496. Hoeg JM, Demosky SJ, Schaefer EJ, Starzl TE, Porter KA, Brewer HB. The effect of portacaval shunt on hepatic lipoprotein metabolism in familial hypercholesterolemia. J Surg Res. 1985 Nov; 39(5):369-77. PMID: 4057999.
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    497. Zannis VI, Ordovas JM, Cladaras C, Cole FS, Forbes G, Schaefer EJ. mRNA and apolipoprotein E synthesis abnormalities in peripheral blood monocyte macrophages in familial apolipoprotein E deficiency. J Biol Chem. 1985 Oct 25; 260(24):12891-4. PMID: 2997147.
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    498. Wilson PW, Zech LA, Gregg RE, Schaefer EJ, Hoeg JM, Sprecher DL, Brewer HB. Estimation of VLDL cholesterol in hyperlipidemia. Clin Chim Acta. 1985 Oct 15; 151(3):285-91. PMID: 3863729.
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    499. Schaefer EJ, Ordovas JM, Law SW, Ghiselli G, Kashyap ML, Srivastava LS, Heaton WH, Albers JJ, Connor WE, Lindgren FT, et al. Familial apolipoprotein A-I and C-III deficiency, variant II. J Lipid Res. 1985 Sep; 26(9):1089-101. PMID: 3934306.
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    500. Libby P, Miao P, Ordovas JM, Schaefer EJ. Lipoproteins increase growth of mitogen-stimulated arterial smooth muscle cells. J Cell Physiol. 1985 Jul; 124(1):1-8. PMID: 3930513.
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    501. Schaefer EJ, Levy RI. Pathogenesis and management of lipoprotein disorders. N Engl J Med. 1985 May 16; 312(20):1300-10. PMID: 3887163.
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    502. Sprecher DL, Hoeg JM, Schaefer EJ, Zech LA, Gregg RE, Lakatos E, Brewer HB. The association of LDL receptor activity, LDL cholesterol level, and clinical course in homozygous familial hypercholesterolemia. Metabolism. 1985 Mar; 34(3):294-9. PMID: 3856094.
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    503. Hoeg JM, Demosky SJ, Gregg RE, Schaefer EJ, Brewer HB. Distinct hepatic receptors for low density lipoprotein and apolipoprotein E in humans. Science. 1985 Feb 15; 227(4688):759-61. PMID: 2982214.
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    504. Bojanovski D, Gregg RE, Ghiselli G, Schaefer EJ, Light JA, Brewer HB. Human apolipoprotein A-I isoprotein metabolism: proapoA-I conversion to mature apoA-I. J Lipid Res. 1985 Feb; 26(2):185-93. PMID: 3989377.
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    505. Gregg RE, Zech LA, Schaefer EJ, Brewer HB. Apolipoprotein E metabolism in normolipoproteinemic human subjects. J Lipid Res. 1984 Nov; 25(11):1167-76. PMID: 6520540.
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    506. Hoeg JM, Schaefer EJ, Romano CA, Bou E, Pikus AM, Zech LA, Bailey KR, Gregg RE, Wilson PW, Sprecher DL, et al. Neomycin and plasma lipoproteins in type II hyperlipoproteinemia. Clin Pharmacol Ther. 1984 Oct; 36(4):555-65. PMID: 6383687.
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    507. Sprecher DL, Schaefer EJ, Kent KM, Gregg RE, Zech LA, Hoeg JM, McManus B, Roberts WC, Brewer HB. Cardiovascular features of homozygous familial hypercholesterolemia: analysis of 16 patients. Am J Cardiol. 1984 Jul 1; 54(1):20-30. PMID: 6331147.
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    508. Schaefer EJ. Clinical, biochemical, and genetic features in familial disorders of high density lipoprotein deficiency. Arteriosclerosis. 1984 Jul-Aug; 4(4):303-22. PMID: 6431953.
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    509. Newman RP, Schaefer EJ, Thomas CB, Oldfield EH. Abetalipoproteinemia and metastatic spinal cord glioblastoma. Arch Neurol. 1984 May; 41(5):554-6. PMID: 6326713.
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    510. Bieri JG, Hoeg JM, Schaefer EJ, Zech LA, Brewer HB. Vitamin A and vitamin E replacement in abetalipoproteinemia. Ann Intern Med. 1984 Feb; 100(2):238-9. PMID: 6691669.
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    511. Hoeg JM, Demosky SJ, Schaefer EJ, Starzl TE, Brewer HB. Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects. J Clin Invest. 1984 Feb; 73(2):429-36. PMID: 6321555; PMCID: PMC425034.
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    512. Osborne JC, Schaefer EJ, Powell GM, Lee NS, Zech LA. Molecular properties of radioiodinated apolipoprotein A-I. J Biol Chem. 1984 Jan 10; 259(1):347-53. PMID: 6423628.
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    513. Fleischmajer R, Schaefer EJ, Gal AE, Pentchev PG, Tint GS. Normolipemic subcutaneous xanthomatosis. Am J Med. 1983 Dec; 75(6):1065-70. PMID: 6650539.
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    514. Starzl TE, Chase HP, Ahrens EH, McNamara DJ, Bilheimer DW, Schaefer EJ, Rey J, Porter KA, Stein E, Francavilla A, Benson LN. Portacaval shunt in patients with familial hypercholesterolemia. Ann Surg. 1983 Sep; 198(3):273-83. PMID: 6615051; PMCID: PMC1353292.
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    515. Schaefer EJ, Triche TJ, Zech LA, Stein LA, Kemeny MM, Brennan MF, Brewer HB. Massive omental reticuloendothelial cell lipid uptake in Tangier disease after splenectomy. Am J Med. 1983 Sep; 75(3):521-6. PMID: 6614036.
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    516. Schaefer EJ, Foster DM, Zech LA, Lindgren FT, Brewer HB, Levy RI. The effects of estrogen administration on plasma lipoprotein metabolism in premenopausal females. J Clin Endocrinol Metab. 1983 Aug; 57(2):262-7. PMID: 6408108.
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    517. Meng MS, Gregg RE, Schaefer EJ, Hoeg JM, Brewer HB. Presence of two forms of apolipoprotein B in patients with dyslipoproteinemia. J Lipid Res. 1983 Jul; 24(7):803-9. PMID: 6631214.
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    518. Ghiselli G, Schaefer EJ, Light JA, Brewer HB. Apolipoprotein A-I isoforms in human lymph: effect of fat absorption. J Lipid Res. 1983 Jun; 24(6):731-6. PMID: 6411847.
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    519. Brewer HB, Zech LA, Gregg RE, Schwartz D, Schaefer EJ. NIH conference. Type III hyperlipoproteinemia: diagnosis, molecular defects, pathology, and treatment. Ann Intern Med. 1983 May; 98(5 Pt 1):623-40. PMID: 6846977.
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    520. Schaefer EJ, Woo R, Kibata M, Bjornsen L, Schreibman PH. Mobilization of triglyceride but not cholesterol or tocopherol from human adipocytes during weight reduction. Am J Clin Nutr. 1983 May; 37(5):749-54. PMID: 6846213.
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    521. White RM, Schaefer EJ, Papadopoulos NM. The effect of growth hormone administration on lipids and lipoproteins in growth hormone-deficient patients. Proc Soc Exp Biol Med. 1983 May; 173(1):63-7. PMID: 6574521.
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    522. Sweet JB, Callihan MD, Schaefer EJ, Tarpley TM. Tangier disease with oral abnormalities. Int J Oral Surg. 1983 Apr; 12(2):110-4. PMID: 6409822.
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    523. Jahn CE, Osborne JC, Schaefer EJ, Brewer HB. Activation of the enzymic activity of hepatic lipase by apolipoprotein A-II. Characterization of a major component of high density lipoprotein as the activating plasma component in vitro. Eur J Biochem. 1983 Mar 1; 131(1):25-9. PMID: 6403350.
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    524. Zech LA, Schaefer EJ, Bronzert TJ, Aamodt RL, Brewer HB. Metabolism of human apolipoproteins A-I and A-II: compartmental models. J Lipid Res. 1983 Jan; 24(1):60-71. PMID: 6403641.
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    525. Spiegel RJ, Schaefer EJ, Magrath IT, Edwards BK. Fluorescence polarization as a parameter of plasma lipids in patients with hematologic malignancies. Leuk Res. 1983; 7(5):647-54. PMID: 6645602.
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    526. Schaefer EJ, Wetzel MG, Bengtsson G, Scow RO, Brewer HB, Olivecrona T. Transfer of human lymph chylomicron constituents to other lipoprotein density fractions during in vitro lipolysis. J Lipid Res. 1982 Dec; 23(9):1259-73. PMID: 7161556.
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    527. Schaefer EJ, Kay LL, Zech LA, Brewer HB. Tangier disease. High density lipoprotein deficiency due to defective metabolism of an abnormal apolipoprotein A-i (ApoA-ITangier). J Clin Invest. 1982 Nov; 70(5):934-45. PMID: 7130397; PMCID: PMC370306.
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    528. Ghiselli G, Gregg RE, Zech LA, Schaefer EJ, Brewer HB. Phenotype study of apolipoprotein E isoforms in hyperlipoproteinaemic patients. Lancet. 1982 Aug 21; 2(8295):405-7. PMID: 6124804.
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    529. Ghiselli G, Schaefer EJ, Zech LA, Gregg RE, Brewer HB. Increased prevalence of apolipoprotein E4 in type V hyperlipoproteinemia. J Clin Invest. 1982 Aug; 70(2):474-7. PMID: 7096573; PMCID: PMC371257.
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    530. Schaefer EJ, Zech LA, Jenkins LL, Bronzert TJ, Rubalcaba EA, Lindgren FT, Aamodt RL, Brewer HB. Human apolipoprotein A-I and A-II metabolism. J Lipid Res. 1982 Aug; 23(6):850-62. PMID: 6813411.
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    531. Morrow JS, Schaefer EJ, Huston DP, Rosen SW. POEMS syndrome: studies in a patient with an IgG-kappa M protein but no polyneuropathy. Arch Intern Med. 1982 Jun; 142(6):1231-4. PMID: 6807233.
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    532. Spiegel RJ, Schaefer EJ, Magrath IT, Edwards BK. Plasma lipid alterations in leukemia and lymphoma. Am J Med. 1982 May; 72(5):775-82. PMID: 7081275.
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    533. Kay LL, Ronan R, Schaefer EJ, Brewer HB. Tangier disease: a structural defect in apolipoprotein A-I (apoA-I Tangier). Proc Natl Acad Sci U S A. 1982 Apr; 79(8):2485-9. PMID: 6806810; PMCID: PMC346223.
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    534. Schaefer EJ, Cooney CL. Production of Maltase by Wild-Type and a Constitutive Mutant of Saccharomyces italicus. Appl Environ Microbiol. 1982 Jan; 43(1):75-80. PMID: 16345932.
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    535. Schaefer EJ, Heaton WH, Wetzel MG, Brewer HB. Plasma apolipoprotein A-1 absence associated with a marked reduction of high density lipoproteins and premature coronary artery disease. Arteriosclerosis. 1982 Jan-Feb; 2(1):16-26. PMID: 6800349.
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    536. Ghiselli G, Schaefer EJ, Gascon P, Breser HB. Type III hyperlipoproteinemia associated with apolipoprotein E deficiency. Science. 1981 Dec 11; 214(4526):1239-41. PMID: 6795720.
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    537. Corash L, Andersen J, Poindexter BJ, Schaefer EJ. Platelet function and survival in patients wit severe hypercholesterolemia. Arteriosclerosis. 1981 Nov-Dec; 1(6):443-8. PMID: 7347208.
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    538. Schaefer EJ, Levy RI, Ernst ND, Van Sant FD, Brewer HB. The effects of low cholesterol, high polyunsaturated fat, and low fat diets on plasma lipid and lipoprotein cholesterol levels in normal and hypercholesterolemic subjects. Am J Clin Nutr. 1981 Sep; 34(9):1758-63. PMID: 6945041.
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    539. Jahn CE, Osborne JC, Schaefer EJ, Brewer HB. In vitro activation of the enzymic activity of hepatic lipase by apoA-II. FEBS Lett. 1981 Aug 31; 131(2):366-8. PMID: 6795058.
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    540. Alaupovic P, Schaefer EJ, McConathy WJ, Fesmire JD, Brewer HB. Plasma apolipoprotein concentrations in familial apolipoprotein A-I and A-II deficiency (Tangier disease). Metabolism. 1981 Aug; 30(8):805-9. PMID: 6790903.
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    541. Berman MD, Ishak KG, Schaefer EJ, Barnes S, Jones EA. Syndromatic hepatic ductular hypoplasia (arteriohepatic dysplasia): a clinical and hepatic histologic study of three patients. Dig Dis Sci. 1981 Jun; 26(6):485-97. PMID: 7238269.
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    542. Anderson DW, Schaefer EJ, Bronzert TJ, Lindgren FT, Forte T, Starzl TE, Niblack GD, Zech LA, Brewer HB. Transport of apolipoproteins A-I and A-II by human thoracic duct lymph. J Clin Invest. 1981 Mar; 67(3):857-66. PMID: 7204560; PMCID: PMC370637.
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    543. Gregg RE, Zech LA, Schaefer EJ, Brewer HB. Type III hyperlipoproteinemia: defective metabolism of an abnormal apolipoprotein E. Science. 1981 Feb 6; 211(4482):584-6. PMID: 7455696.
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    544. Schaefer EJ, Anderson DW, Zech LA, Lindgren FT, Bronzert TB, Rubalcaba EA, Brewer HB. Metabolism of high density lipoprotein subfractions and constituents in Tangier disease following the infusion of high density lipoproteins. J Lipid Res. 1981 Feb; 22(2):217-28. PMID: 6787156.
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    545. Papadopoulos NM, Schaefer EJ, Anderson DW. Demonstration of heterogeneity in a high-density lipoprotein subfraction. Clin Chem. 1981 Jan; 27(1):197-8. PMID: 7449108.
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    546. Lipson LC, Bonow RO, Schaefer EJ, Brewer HB, Lindgren FT. Effect of exercise conditioning on plasma high density lipoproteins and other lipoproteins. Atherosclerosis. 1980 Dec; 37(4):529-38. PMID: 7458999.
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    547. Nakaya Y, Schaefer EJ, Brewer HB. Activation of human post heparin lipoprotein lipase by apolipoprotein H (beta 2-glycoprotein I). Biochem Biophys Res Commun. 1980 Aug 14; 95(3):1168-72. PMID: 7417307.
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    548. Schaefer EJ, Zech LA, Schwartz DE, Brewer HB. Coronary heart disease prevalence and other clinical features in familial high-density lipoprotein deficiency (Tangier disease). Ann Intern Med. 1980 Aug; 93(2):261-6. PMID: 7406376.
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    549. Ernst N, Fisher M, Bowen P, Schaefer EJ, Levy RI. Changes in plasma lipids and lipoproteins after a modified fat diet. Lancet. 1980 Jul 19; 2(8186):111-3. PMID: 6105293.
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    550. Reinertsen JL, Schaefer EJ, Brewer HB, Moutsopoulos HM. Sicca-like syndrome in type V hyperlipoproteinemia. Arthritis Rheum. 1980 Jan; 23(1):114-8. PMID: 7352931.
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    551. Chu FC, Kuwabara T, Cogan DG, Schaefer EJ, Brewer HB. Ocular manifestations of familial high-density lipoprotein deficiency (Tangier disease). Arch Ophthalmol. 1979 Oct; 97(10):1926-8. PMID: 226043.
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    552. Schaefer EJ, Foster DM, Jenkins LL, Lindgren FT, Berman M, Levy RI, Brewer HB. The composition and metabolism of high density lipoprotein subfractions. Lipids. 1979 May; 14(5):511-22. PMID: 222991.
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    553. Schaefer EJ, Levy RI. Composition and metabolism of high-density lipoproteins. Prog Biochem Pharmacol. 1979; 15:200-15. PMID: 224395.
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    554. Schaefer EJ, Blum CB, Levy RI, Jenkins LL, Alaupovic P, Foster DM, Brewer HB. Metabolism of high-density lipoprotein apolipoproteins in Tangier disease. N Engl J Med. 1978 Oct 26; 299(17):905-10. PMID: 211412.
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    555. Schaefer EJ, Levy RI, Anderson DW, Danner RN, Brewer HB, Blackwelder WC. Plasma-triglycerides in regulation of H.D.L.-cholesterol levels. Lancet. 1978 Aug 19; 2(8086):391-3. PMID: 79759.
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    556. Schaefer EJ, Eisenberg S, Levy RI. Lipoprotein apoprotein metabolism. J Lipid Res. 1978 Aug; 19(6):667-87. PMID: 211170.
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    557. Schaefer EJ, Jenkins LL, Brewer HB. Human chylomicron apolipoprotein metabolism. Biochem Biophys Res Commun. 1978 Jan 30; 80(2):405-12. PMID: 414755.
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    558. Staheli LT, Duncan WR, Schaefer E. Growth alterations in the hemiplegic child. A study of femoral anteversion, neck-shaft angle, hip rotation, C.E. angle, limb length and circumference in 50 hemiplegic children. Clin Orthop Relat Res. 1968 Sep-Oct; 60:205-12. PMID: 5703292.
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