Keywords
Last Name
Institution

Jay S. Steingrub

TitleProfessor
InstitutionBaystate Medical Center
DepartmentMedicine
AddressCritical Care Medicine
Baystate Medical Center
759 Chestnut Street
Springfield MA 01199-0001
Phone(413) 794-5439
Fax(413) 794-5389
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Limaye AP, Stapleton RD, Peng L, Gunn SR, Kimball LE, Hyzy R, Exline MC, Files DC, Morris PE, Frankel SK, Mikkelsen ME, Hite D, Enfield KB, Steingrub J, O'Brien J, Parsons PE, Cuschieri J, Wunderink RG, Hotchkin DL, Chen YQ, Rubenfeld GD, Boeckh M. Effect of Ganciclovir on IL-6 Levels Among Cytomegalovirus-Seropositive Adults With Critical Illness: A Randomized Clinical Trial. JAMA. 2017 Aug 22; 318(8):731-740. PMID: 28829877.
      View in: PubMed
    2. Chiarchiaro J, Ernecoff NC, Scheunemann LP, Hough CL, Carson SS, Peterson MW, Anderson WG, Steingrub JS, Arnold RM, White DB. Physicians Rarely Elicit Critically Ill Patients' Previously Expressed Treatment Preferences in Intensive Care Units. Am J Respir Crit Care Med. 2017 Jul 15; 196(2):242-245. PMID: 28707977.
      View in: PubMed
    3. Stefan MS, Nathanson BH, Lagu T, Priya A, Pekow PS, Steingrub JS, Hill NS, Goldberg RJ, Kent DM, Lindenauer PK. Outcomes of Noninvasive and Invasive Ventilation in Patients Hospitalized with Asthma Exacerbation. Ann Am Thorac Soc. 2016 Jul; 13(7):1096-104. PMID: 27070493.
      View in: PubMed
    4. Ernecoff NC, Witteman HO, Chon K, Chen YI, Buddadhumaruk P, Chiarchiaro J, Shotsberger KJ, Shields AM, Myers BA, Hough CL, Carson SS, Lo B, Matthay MA, Anderson WG, Peterson MW, Steingrub JS, Arnold RM, White DB. Key stakeholders' perceptions of the acceptability and usefulness of a tablet-based tool to improve communication and shared decision making in ICUs. J Crit Care. 2016 Jun; 33:19-25. PMID: 27037049.
      View in: PubMed
    5. Stefan MS, Nathanson BH, Priya A, Pekow PS, Lagu T, Steingrub JS, Hill NS, Goldberg RJ, Kent DM, Lindenauer PK. Hospitals' Patterns of Use of Noninvasive Ventilation in Patients With Asthma Exacerbation. Chest. 2016 Mar; 149(3):729-36. PMID: 26836902.
      View in: PubMed
    6. Stefan MS, Nathanson BH, Higgins TL, Steingrub JS, Lagu T, Rothberg MB, Lindenauer PK. Comparative Effectiveness of Noninvasive and Invasive Ventilation in Critically Ill Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Crit Care Med. 2015 Jul; 43(7):1386-94. PMID: 25768682.
      View in: PubMed
    7. Anderson WG, Cimino JW, Ernecoff NC, Ungar A, Shotsberger KJ, Pollice LA, Buddadhumaruk P, Carson SS, Curtis JR, Hough CL, Lo B, Matthay MA, Peterson MW, Steingrub JS, White DB. A Multicenter Study of Key Stakeholders' Perspectives on Communicating with Surrogates about Prognosis in Intensive Care Units. Ann Am Thorac Soc. 2015 Feb; 12(2):142-52. PMID: 25521191.
      View in: PubMed
    8. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med. 2014 Jun 5; 370(23):2191-200. PMID: 24835849.
      View in: PubMed
    9. Lagu T, Stefan MS, Haessler S, Higgins TL, Rothberg MB, Nathanson BH, Hannon NS, Steingrub JS, Lindenauer PK. The impact of hospital-onset Clostridium difficile infection on outcomes of hospitalized patients with sepsis. J Hosp Med. 2014 Jul; 9(7):411-7. PMID: 24715578; NIHMSID: NIHMS579586 [Available on 07/01/15].
      View in: PubMed
    10. Steingrub JS, Lagu T, Rothberg MB, Nathanson BH, Raghunathan K, Lindenauer PK. Treatment with neuromuscular blocking agents and the risk of in-hospital mortality among mechanically ventilated patients with severe sepsis. Crit Care Med. 2014 Jan; 42(1):90-6. PMID: 23982029.
      View in: PubMed
    11. Lagu T, Rothberg MB, Nathanson BH, Hannon NS, Steingrub JS, Lindenauer PK. Contributors to variation in hospital spending for critically ill patients with sepsis. Healthc (Amst). 2013 Jun; 1(1-2):30-6. PMID: 26249637.
      View in: PubMed
    12. Stefan MS, Shieh MS, Pekow PS, Rothberg MB, Steingrub JS, Lagu T, Lindenauer PK. Epidemiology and outcomes of acute respiratory failure in the United States, 2001 to 2009: a national survey. J Hosp Med. 2013 Feb; 8(2):76-82. PMID: 23335231; NIHMSID: NIHMS424666.
      View in: PubMed
    13. Agrawal A, Zhuo H, Brady S, Levitt J, Steingrub J, Siegel MD, Soto G, Peterson MW, Chesnutt MS, Matthay MA, Liu KD. Pathogenetic and predictive value of biomarkers in patients with ALI and lower severity of illness: results from two clinical trials. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 15; 303(8):L634-9. PMID: 22865551; PMCID: PMC3469636.
      View in: PubMed
      View in: PubMed Central
    14. Lagu T, Rothberg MB, Nathanson BH, Steingrub JS, Lindenauer PK. Incorporating initial treatments improves performance of a mortality prediction model for patients with sepsis. Pharmacoepidemiol Drug Saf. 2012 May; 21 Suppl 2:44-52. PMID: 22552979.
      View in: PubMed
    15. Lagu T, Rothberg MB, Shieh MS, Pekow PS, Steingrub JS, Lindenauer PK. What is the best method for estimating the burden of severe sepsis in the United States? J Crit Care. 2012 Aug; 27(4):414.e1-9. PMID: 22516143.
      View in: PubMed
    16. Blagev DP, Hirshberg EL, Sward K, Thompson BT, Brower R, Truwit J, Hite D, Steingrub J, Orme JF, Clemmer TP, Weaver LK, Thomas F, Grissom CK, Sorenson D, Sittig DF, Wallace CJ, East TD, Warner HR, Morris AH. The evolution of eProtocols that enable reproducible clinical research and care methods. J Clin Monit Comput. 2012 Aug; 26(4):305-17. PMID: 22491960.
      View in: PubMed
    17. Andrzejewski C, Popovsky MA, Stec TC, Provencher J, O'Hearn L, Visintainer P, Steingrub J. Hemotherapy bedside biovigilance involving vital sign values and characteristics of patients with suspected transfusion reactions associated with fluid challenges: can some cases of transfusion-associated circulatory overload have proinflammatory aspects? Transfusion. 2012 Nov; 52(11):2310-20. PMID: 23216230.
      View in: PubMed
    18. Lagu T, Rothberg MB, Shieh MS, Pekow PS, Steingrub JS, Lindenauer PK. Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007. Crit Care Med. 2012 Mar; 40(3):754-61. PMID: 21963582.
      View in: PubMed
    19. Morris PE, Steingrub JS, Huang BY, Tang S, Liu PM, Rhode PR, Wong HC. A phase I study evaluating the pharmacokinetics, safety and tolerability of an antibody-based tissue factor antagonist in subjects with acute lung injury or acute respiratory distress syndrome. BMC Pulm Med. 2012; 12:5. PMID: 22340260; PMCID: PMC3299584.
      View in: PubMed
      View in: PubMed Central
    20. Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA. 2012 Feb 22; 307(8):795-803. PMID: 22307571; NIHMSID: NIHMS496761.
      View in: PubMed
    21. Lagu T, Rothberg MB, Nathanson BH, Pekow PS, Steingrub JS, Lindenauer PK. Variation in the care of septic shock: the impact of patient and hospital characteristics. J Crit Care. 2012 Aug; 27(4):329-36. PMID: 22300489.
      View in: PubMed
    22. Liu KD, Thompson BT, Ancukiewicz M, Steingrub JS, Douglas IS, Matthay MA, Wright P, Peterson MW, Rock P, Hyzy RC, Anzueto A, Truwit JD. Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med. 2011 Dec; 39(12):2665-71. PMID: 21785346; NIHMSID: NIHMS310507.
      View in: PubMed
    23. Lagu T, Lindenauer PK, Rothberg MB, Nathanson BH, Pekow PS, Steingrub JS, Higgins TL. Development and validation of a model that uses enhanced administrative data to predict mortality in patients with sepsis. Crit Care Med. 2011 Nov; 39(11):2425-30. PMID: 22005222.
      View in: PubMed
    24. Rice TW, Wheeler AP, Thompson BT, deBoisblanc BP, Steingrub J, Rock P. Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA. 2011 Oct 12; 306(14):1574-81. PMID: 21976613; NIHMSID: NIHMS496772.
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    25. Randomized, placebo-controlled clinical trial of an aerosolized ß2-agonist for treatment of acute lung injury. Am J Respir Crit Care Med. 2011 Sep 1; 184(5):561-8. PMID: 21562125; PMCID: PMC3175548.
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      View in: PubMed Central
    26. Rice TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P, Ely EW. Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status. Crit Care. 2011; 15(2):R86. PMID: 21385351; PMCID: PMC3219344.
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      View in: PubMed Central
    27. Lagu T, Rothberg MB, Nathanson BH, Pekow PS, Steingrub JS, Lindenauer PK. The relationship between hospital spending and mortality in patients with sepsis. Arch Intern Med. 2011 Feb 28; 171(4):292-9. PMID: 21357803.
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    28. Steingrub JS, Cheatham ML, Woodward B, Wang HT, Effron MB. A prospective, observational study of Xigris Use in the United States (XEUS). J Crit Care. 2010 Dec; 25(4):660.e9-16. PMID: 20435433.
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    29. Lindenauer PK, Rothberg MB, Nathanson BH, Pekow PS, Steingrub JS. Activated protein C and hospital mortality in septic shock: a propensity-matched analysis. Crit Care Med. 2010 Apr; 38(4):1101-7. PMID: 20154607.
      View in: PubMed
    30. Kinasewitz GT, Privalle CT, Imm A, Steingrub JS, Malcynski JT, Balk RA, DeAngelo J. Multicenter, randomized, placebo-controlled study of the nitric oxide scavenger pyridoxalated hemoglobin polyoxyethylene in distributive shock. Crit Care Med. 2008 Jul; 36(7):1999-2007. PMID: 18552688.
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    31. Liu KD, Levitt J, Zhuo H, Kallet RH, Brady S, Steingrub J, Tidswell M, Siegel MD, Soto G, Peterson MW, Chesnutt MS, Phillips C, Weinacker A, Thompson BT, Eisner MD, Matthay MA. Randomized clinical trial of activated protein C for the treatment of acute lung injury. Am J Respir Crit Care Med. 2008 Sep 15; 178(6):618-23. PMID: 18565951; PMCID: PMC2542435.
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      View in: PubMed Central
    32. Morris AH, Orme J, Truwit JD, Steingrub J, Grissom C, Lee KH, Li GL, Thompson BT, Brower R, Tidswell M, Bernard GR, Sorenson D, Sward K, Zheng H, Schoenfeld D, Warner H. A replicable method for blood glucose control in critically Ill patients. Crit Care Med. 2008 Jun; 36(6):1787-95. PMID: 18520641.
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    33. Thompson BT, Orme JF, Zheng H, Luckett PM, Truwit JD, Willson DF, Duncan Hite R, Brower RG, Bernard GR, Curley MA, Steingrub JS, Sorenson DK, Sward K, Hirshberg E, Morris AH. Multicenter validation of a computer-based clinical decision support tool for glucose control in adult and pediatric intensive care units. J Diabetes Sci Technol. 2008 May; 2(3):357-68. PMID: 19885199; PMCID: PMC2769731.
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      View in: PubMed Central
    34. Wheeler A, Steingrub J, Schmidt GA, Sanchez P, Jacobi J, Linde-Zwirble W, Bates B, Qualy RL, Woodward B, Zeckel M. A retrospective observational study of drotrecogin alfa (activated) in adults with severe sepsis: comparison with a controlled clinical trial. Crit Care Med. 2008 Jan; 36(1):14-23. PMID: 18158435.
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    35. Steingrub JS. Adding up the zeros. J Intensive Care Med. 2006 May-Jun; 21(3):188-90. PMID: 16672641.
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    36. Higgins TL, Steingrub JS, Tereso GJ, Tidswell MA, McGee WT. Drotrecogin alfa (activated) in sepsis: initial experience with patient selection, cost, and clinical outcomes. J Intensive Care Med. 2005 Nov-Dec; 20(6):339-45. PMID: 16280407.
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    37. Guntupalli SR, Steingrub J. Hepatic disease and pregnancy: an overview of diagnosis and management. Crit Care Med. 2005 Oct; 33(10 Suppl):S332-9. PMID: 16215356.
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    38. Zeiher BG, Steingrub J, Laterre PF, Dmitrienko A, Fukiishi Y, Abraham E. LY315920NA/S-5920, a selective inhibitor of group IIA secretory phospholipase A2, fails to improve clinical outcome for patients with severe sepsis. Crit Care Med. 2005 Aug; 33(8):1741-8. PMID: 16096451.
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    39. Levy H, Small D, Heiselman DE, Riker R, Steingrub J, Chen R, Qualy RL, Darstein C, Mongan E. Obesity does not alter the pharmacokinetics of drotrecogin alfa (activated) in severe sepsis. Ann Pharmacother. 2005 Feb; 39(2):262-7. PMID: 15632220.
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    40. Steingrub JS. Pregnancy-associated severe liver dysfunction. Crit Care Clin. 2004 Oct; 20(4):763-76, xi. PMID: 15388201.
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    41. López A, Lorente JA, Steingrub J, Bakker J, McLuckie A, Willatts S, Brockway M, Anzueto A, Holzapfel L, Breen D, Silverman MS, Takala J, Donaldson J, Arneson C, Grove G, Grossman S, Grover R. Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock. Crit Care Med. 2004 Jan; 32(1):21-30. PMID: 14707556.
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    42. Steingrub JS. Steroids and drotrecogin alfa (activated) for severe sepsis. Chest. 2003 Nov; 124(5):2033. PMID: 14605088.
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    43. Steingrub JS, Tidswell M, Higgins TL. Hemodynamic consequences of heart-lung interactions. J Intensive Care Med. 2003 Mar-Apr; 18(2):92-9. PMID: 15189655.
      View in: PubMed
    44. Nathanson BH, Higgins TL, Giglio RJ, Munshi IA, Steingrub JS. An exploratory study using data envelopment analysis to assess neurotrauma patients in the intensive care unit. Health Care Manag Sci. 2003 Feb; 6(1):43-55. PMID: 12638926.
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    45. Higgins TL, McGee WT, Steingrub JS, Rapoport J, Lemeshow S, Teres D. Early indicators of prolonged intensive care unit stay: impact of illness severity, physician staffing, and pre-intensive care unit length of stay. Crit Care Med. 2003 Jan; 31(1):45-51. PMID: 12544992.
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    46. Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med. 2001 Mar 8; 344(10):699-709. PMID: 11236773.
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    47. Munshi IA, Steingrub JS, Wolpert L. Small bowel necrosis associated with early postoperative jejunal tube feeding in a trauma patient. J Trauma. 2000 Jul; 49(1):163-5. PMID: 10912876.
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    48. Rapoport J, Teres D, Steingrub J, Higgins T, McGee W, Lemeshow S. Patient characteristics and ICU organizational factors that influence frequency of pulmonary artery catheterization. JAMA. 2000 May 17; 283(19):2559-67. PMID: 10815120.
      View in: PubMed
    49. Steingrub JS. Bioelectrical impedance monitoring: is this a bull market for electric utilities? Crit Care Med. 2000 Jan; 28(1):273-5. PMID: 10667548.
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    50. Abraham E, Baughman R, Fletcher E, Heard S, Lamberti J, Levy H, Nelson L, Rumbak M, Steingrub J, Taylor J, Park YC, Hynds JM, Freitag J. Liposomal prostaglandin E1 (TLC C-53) in acute respiratory distress syndrome: a controlled, randomized, double-blind, multicenter clinical trial. TLC C-53 ARDS Study Group. Crit Care Med. 1999 Aug; 27(8):1478-85. PMID: 10470753.
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    51. Steingrub JS, Mundt DJ. Blood glucose and neurologic outcome with global brain ischemia. Crit Care Med. 1996 May; 24(5):802-6. PMID: 8706457.
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    52. Navab F, Steingrub J. Stress ulcer: is routine prophylaxis necessary? Am J Gastroenterol. 1995 May; 90(5):708-12. PMID: 7733073.
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    53. Steingrub JS, Celoria G, Vickers-Lahti M, Teres D, Bria W. Therapeutic impact of pulmonary artery catheterization in a medical/surgical ICU. Chest. 1991 Jun; 99(6):1451-5. PMID: 2036830.
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    54. Celoria G, Steingrub JS, Vickers-Lahti M, Teres D, Stein KL, Fink M, Friedmann P. Clinical assessment of hemodynamic values in two surgical intensive care units. Effects on therapy. Arch Surg. 1990 Aug; 125(8):1036-9. PMID: 2378556.
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    55. Steingrub JS, Sweet S, Teres D. Crack-induced rhabdomyolysis. Crit Care Med. 1989 Oct; 17(10):1073-4. PMID: 2791571.
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    56. Mitchell SC, Steingrub J. The changing clinical trials scene: the role of the IRB. IRB. 1988 Jul-Aug; 10(4):1-5. PMID: 11650078.
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    57. Steingrub JS, Lopez T, Teres D, Steingart R. Amniotic fluid embolism associated with castor oil ingestion. Crit Care Med. 1988 Jun; 16(6):642-3. PMID: 3371030.
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    58. Steingrub JS, Mikolich DJ, Schlaeffer F. Delirium tremens with meningismus. Isr J Med Sci. 1987 Jul; 23(7):839-40. PMID: 3692753.
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    59. Teres D, Steingrub J. Can intermediate care substitute for intensive care? Crit Care Med. 1987 Mar; 15(3):280. PMID: 3816267.
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    60. Steingrub J, Detore A, Teres D. Spontaneous rupture of pulmonary artery. Crit Care Med. 1987 Mar; 15(3):270-1. PMID: 3816263.
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    61. Celoria G, Steingrub J, Dawson JA, Teres D. Oliguria from high intra-abdominal pressure secondary to ovarian mass. Crit Care Med. 1987 Jan; 15(1):78-9. PMID: 3792018.
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    62. Braden GL, Steingrub JS, Teres D. Treatment of hypophosphatemia. Crit Care Med. 1985 Nov; 13(11):995. PMID: 4053651.
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    63. Steingrub JS, Bria W, Teres D. Usefulness of pulmonary artery catheterization in the ICU. Crit Care Med. 1985 Jul; 13(7):611-2. PMID: 4006505.
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    64. Lemeshow S, Teres D, Pastides H, Avrunin JS, Steingrub JS. A method for predicting survival and mortality of ICU patients using objectively derived weights. Crit Care Med. 1985 Jul; 13(7):519-25. PMID: 4006490.
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    This website was supported by the National Center for Research Resources Award Number UL1RR025752 and the National Center for Advancing Translational Sciences, National Institutes of Health, Award Numbers UL1TR000073 and UL1TR001064. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH.

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